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\u7de8\u8f2f\uff1a\u738b\u7fe0\u9e97<\/p>\n<\/p>\n

https:\/\/video3.mingpao.com\/201612\/HET20161213_01.mp4\u9280\u5c51\u75c5\u4e0d\u6703\u50b3\u67d3;https:\/\/video3.mingpao.com\/201612\/HET20161213_02.mp4\u9280\u5c51\u75c5\u5fb5\u72c0;https:\/\/video3.mingpao.com\/201612\/HET20161213_03.mp4\u9280\u5c51\u75c5 \u773c\u775b \u60c5\u7dd2\u4e00\u540c\u767c\u75c5;https:\/\/video3.mingpao.com\/201612\/HET20161213_04.mp4\u8ab0\u4eba\u9069\u7528\u751f\u7269\u88fd\u5291\uff1f;https:\/\/health2.mingpao.com\/ftp\/Health2\/20170116\/news\/_16ya101.jpg\uff08\u5716\uff1a\u937e\u6797\u679d\uff09;<\/inline><\/p>\n","protected":false},"excerpt":{"rendered":"

【明報專訊】不少人都有腰痛、膝痛、手指關節痛等「小毛病」,覺得是小事而忽略,休息一下就會康復,但沒想過可能是其他疾病的「警號」。<\/p>\n

銀屑病,俗稱牛皮癬,看似是皮膚問題,但近年愈來愈多研究發現,患者同時出現多種共病纏身,關節疼痛、心血管疾病、抑鬱、虹膜炎等。因此不要忽略這些「警號」,及早求醫以全面控制病情。<\/p>\n

一名年約40歲的女傳道人,每日需要步行三層樓梯回教堂工作,患上銀屑病。風濕病科專科醫生余嘉龍指出,「她病發了數月,九成皮膚受影響,有紅、增厚、脫皮等徵狀,受影響範圍極大。另外,因腳跟和膝關節亦受影響,需要輪椅代步」。當她來求診時,不停地哭,有抑鬱徵狀,不願意上班。<\/p>\n

另一名老婆婆病人,因為膝痛向骨科求診,以為是勞損退化需要更換關節。然而,因為病情惡化速度快,不似是一般關節退化,引來醫生懷疑;再經詳細檢查才發現是銀屑病關節炎。<\/p>\n

發病高峰:20-30歲及50-60歲<\/p>\n

銀屑病在全球的發病率為2%。余嘉龍指出,香港的發病率則約為0.3%至0.6%,而發病年齡通常分兩個高峰期,最多為20至30歲之間,這個年紀病發與遺傳因素有較大關係;另一個是50至60歲,多是後天因素激發所致。銀屑病早期徵狀,七成人皮膚有脫皮情况,「但亦有三成患者的關節、筋腱首先受到攻擊,增加診斷困難」。<\/p>\n

生物製劑有效紓緩急性發作<\/p>\n

雖然數據顯示,銀屑病在香港的發病率較低,但余嘉龍認為數據未完全反映問題的嚴重性,因為不少病人逃避求診。「過去一直以為,銀屑病人因為皮膚外表受影響,導致抑鬱,患者隱藏自己而不去正視病情;但新的研究發現,銀屑病會影響腦部,因而出現抑鬱。」除了抑鬱,近年發現銀屑病有不少「共病」,如指炎、虹膜炎、血管病變等,「誤導」病人和醫生,因而延誤診斷和治療。<\/p>\n

銀屑病與免疫力失調有關,無法根治。但余嘉龍補充,現時藥物成效亦不斷提高,除了有傳統的免疫系統調節藥物,現時最有效是使用生物製劑。「約十多年前便有生物製劑抗腫瘤壞死因子(anti-TNF)。近年研究發現,控制白細胞介素IL12、IL23、IL17數量,可減低免疫系統對身體的攻擊,所以新的生物製劑都會針對抑制白細胞介素,減輕發炎,同時減低其他併發症的可能性。」<\/p>\n

以上述40歲病人為例,由於她病發速度較快,所以余嘉龍決定使用起效較快的生物製劑,「傳統免疫系統調節藥物,要兩個月才起效,而生物製劑一般可在兩個星期發揮作用,這個病人用藥約兩周之後,可以慢慢行路;一個月後可正常行走,三個月後皮疹全部消失。此時便停止注射生物製劑,改用傳統口服藥,至今沒有復發」。<\/p>\n

文:勞耀全<\/p>\n

圖:鍾林枝、受訪者提供<\/p>\n

編輯:王翠麗<\/p>\n

■有片睇<\/p>\n

想現場直擊家庭醫生睇醫生,可登入 www.mingpaohealth.com\/doc.htm<\/a><\/p>\n

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