{"id":45877,"date":"2024-01-09T12:55:26","date_gmt":"2024-01-09T04:55:26","guid":{"rendered":"\/\/www.afterroberto.com\/?p=45877"},"modified":"2024-01-09T13:00:17","modified_gmt":"2024-01-09T05:00:17","slug":"%e9%a3%9f%e9%81%93%e7%99%8c%e7%97%87%e7%8b%80%e5%90%9e%e5%9a%a5%e5%9b%b0%e9%9b%a3-%e8%bf%91%e5%bf%83%e8%82%ba%e6%b0%a3%e7%ae%a1%e8%85%ab%e7%98%a4%e5%a4%a7","status":"publish","type":"post","link":"\/\/www.afterroberto.com\/%e9%a3%9f%e9%81%93%e7%99%8c%e7%97%87%e7%8b%80%e5%90%9e%e5%9a%a5%e5%9b%b0%e9%9b%a3-%e8%bf%91%e5%bf%83%e8%82%ba%e6%b0%a3%e7%ae%a1%e8%85%ab%e7%98%a4%e5%a4%a7\/","title":{"rendered":"\u98df\u9053\u764c\u75c7\u72c0\u541e\u56a5\u56f0\u96e3 \u8fd1\u5fc3\u80ba\u6c23\u7ba1\u816b\u7624\u5927\u6216\u81f4\u5410\u8840\u547c\u5438\u56f0\u96e3\u00a0"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<p>\u3010\u660e\u5831\u5c08\u8a0a\u3011\u6839\u64da\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc3\u7684\u6578\u64da\u986f\u793a\uff0c\u9999\u6e2f\u904e\u53bb10\u5e74\uff0c\u6bcf\u5e74\u5e73\u5747\u7d04\u6709410\u5b97<a href=\"\/\/www.afterroberto.com\/%e9%a3%9f%e9%81%93%e7%99%8c%e5%be%b5%e5%85%86-%e5%90%9e%e5%9a%a5%e6%9c%89%e7%95%b0%e7%89%a9%e6%84%9f-%e9%80%b2%e9%a3%9f%e5%96%9d%e6%b0%b4%e7%96%bc%e7%97%9b-%e8%83%b8%e9%aa%a8%e5%be%8c%e4%b8%8d\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u98df\u9053\u764c<\/a>\u65b0\u75c7\uff0c\u903e310\u4eba\u6b7b\u65bc\u98df\u9053\u764c\u3002\u98df\u9053\u662f\u4e00\u500b\u7ba1\u72c0\u5668\u5b98\uff0c\u9023\u63a5\u54bd\u5589\u548c\u80c3\u90e8\uff0c\u9577\u7d0425\u81f330\u5398\u7c73\u3002\u98df\u9053\u672c\u8eab\u6c92\u6709\u6d88\u5316\u98df\u7269\u7684\u529f\u80fd\uff0c\u53ea\u662f\u901a\u904e\u8815\u52d5\u5c07\u98df\u7269\u9001\u5230\u80c3\u90e8\u6d88\u5316\u3002\u98df\u9053\u764c\u60a3\u8005\u5e38\u898b\u75c7\u72c0\u662f<a href=\"\/\/www.afterroberto.com\/%e5%90%9e%e5%9a%a5%e5%9b%b0%e9%9b%a3-%e7%b6%93%e5%b8%b8%e6%bf%81%e8%a6%aa-%e8%90%bd%e9%8c%af%e6%a0%bc-%e4%ba%86%e8%a7%a3%e5%90%9e%e5%9a%a5%e5%8b%95%e4%bd%9c4%e9%9a%8e%e6%ae%b5-%e5%8f%8a%e6%97%a9\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u541e\u56a5\u56f0\u96e3<\/a>\uff0c\u4f46\u60a3\u8005\u8a31\u591a\u6642\u6703\u8abf\u7bc0\u9032\u98df\u7fd2\u6163\uff0c\u5982\u54ac\u788e\u4e00\u9ede\u624d\u541e\u56a5\uff0c\u5ffd\u7565\u6cbb\u7642\uff0c\u56e0\u800c\u5c0e\u81f4\u75c5\u60c5\u60e1\u5316\u3002\uff08\u7de8\u6309\uff1a\u98df\u9053\u9130\u8fd1\u6709\u8a31\u591a\u91cd\u8981\u5668\u5b98\uff0c\u5982\u5fc3\u81df\u3001\u80ba\u90e8\u3001\u6c23\u7ba1\u3001\u5927\u52d5\u8108\u7b49\uff0c\u82e5\u816b\u7624\u8f03\u5927\uff0c\u75c5\u4eba\u6709\u53ef\u80fd\u51fa\u73fe\u5410\u8840\u3001\u547c\u5438\u56f0\u96e3\u7b49\u3002\u82e5\u98df\u9053\u764c\u6c92\u6709\u6216\u5df2\u64f4\u6563\uff0c\u5728\u6cbb\u7642\u53c8\u6709\u4ec0\u9ebc\u4e0d\u540c\uff1f\u514d\u75ab\u6cbb\u7642\u6709\u6548\u55ce\uff1f\uff09<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><picture><source srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/2450fa4dc9114855b58715c63baf07b0.webp 524w,\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/2450fa4dc9114855b58715c63baf07b0-300x223.webp 300w,\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/2450fa4dc9114855b58715c63baf07b0-150x111.webp 150w\" sizes=\"(max-width: 524px) 100vw, 524px\" type=\"image\/webp\"><img src=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/2450fa4dc9114855b58715c63baf07b0.jpg\" height=\"389\" width=\"524\" srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/2450fa4dc9114855b58715c63baf07b0.jpg 524w, \/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/2450fa4dc9114855b58715c63baf07b0-300x223.jpg 300w, \/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/2450fa4dc9114855b58715c63baf07b0-150x111.jpg 150w\" sizes=\"(max-width: 524px) 100vw, 524px\" class=\"wp-image-45879 sp-no-webp\" alt=\"\" fetchpriority=\"high\" decoding=\"async\"  > <\/picture><figcaption class=\"wp-element-caption\">&nbsp;\uff08\u8a2d\u8a08\u5716\u7247\uff0c\u6a21\u7279\u5152\u8207\u6587\u4e2d\u63d0\u53ca\u500b\u6848\u7121\u95dc\uff0ckazuma seki@iStockphoto\uff09<\/figcaption><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u98df\u9053\u764c\u5e38\u898b\u75c7\u72c0\u541e\u56a5\u56f0\u96e3 \u9130\u8fd1\u5fc3\u80ba\u6c23\u7ba1\u6216\u5410\u8840\u547c\u5438\u56f0\u96e3<\/strong><\/h2>\n\n\n\n<p>\u738b\u5148\u751f\uff0c74\u6b72\uff0c3\u500b\u6708\u524d\u958b\u59cb\u611f\u5230\u541e\u56a5\u56f0\u96e3\uff0c\u5411\u5916\u79d1\u91ab\u751f\u6c42\u8a3a\uff0c\u80c3\u93e1\u767c\u73fe\u98df\u9053\u6709\u816b\u7624\uff0c\u7d44\u7e54\u5316\u9a57\u78ba\u8a3a\u9c57\u72c0\u98df\u9053\u764c\uff0c\u8f49\u4ecb\u4f86\u5230\u816b\u7624\u79d1\u3002\u6211\u5efa\u8b70\u4ed6\u5148\u505a\u6b63\u96fb\u5b50\u6383\u63cf\uff0c\u4ee5\u80af\u5b9a\u816b\u7624\u6709\u5426\u64f4\u6563\u81f3\u5176\u4ed6\u5730\u65b9\uff0c\u624d\u4f5c\u4e0b\u4e00\u6b65\u7642\u7a0b\u8a08\u5283\u3002\u9019\u4e5f\u5e36\u51fa\u4e86\u4ee5\u4e0b\u554f\u984c\uff1a<br><br>\u98df\u9053\u764c\u60a3\u8005\u591a\u65bc\u521d\u671f\u611f\u5230\u541e\u56a5\u56f0\u96e3\uff0c\u4f46\u60a3\u8005\u8a31\u591a\u6642\u5019\u6703\u4e0d\u81ea\u89ba\u5730\u6539\u8b8a\u9032\u98df\u7fd2\u6163\uff0c\u4f8b\u5982\u54ac\u788e\u4e00\u9ede\u624d\u541e\u56a5\uff0c\u6216\u9032\u98df\u8cea\u5730\u8f03\u8edf\u7684\u98df\u7269\uff0c\u5ffd\u7565\u6cbb\u7642\uff0c\u56e0\u800c\u5c0e\u81f4\u75c5\u60c5\u60e1\u5316\u3002\u60a3\u8005\u9032\u98df\u6642\u4e5f\u53ef\u80fd\u611f\u5230\u80f8\u90e8\u4e0d\u9069\u6216\u75bc\u75db\uff0c\u751a\u81f3\u5614\u5410\uff1b\u7531\u65bc\u60a3\u8005\u7121\u6cd5\u6b63\u5e38\u9032\u98df\uff0c\u6703\u4ee4\u9ad4\u91cd\u4e0b\u964d\u548c\u6d88\u7626\u3002\u98df\u9053\u9130\u8fd1\u6709\u8a31\u591a\u91cd\u8981\u5668\u5b98\uff0c\u5982\u5fc3\u81df\u3001\u80ba\u90e8\u3001\u6c23\u7ba1\u3001\u5927\u52d5\u8108\u7b49\uff0c\u82e5\u816b\u7624\u8f03\u5927\uff0c\u75c5\u4eba\u6709\u53ef\u80fd\u51fa\u73fe\u5410\u8840\u3001\u547c\u5438\u56f0\u96e3\u7b49\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><picture><source srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/376487caa98c45c7be20b251003e788b.webp 319w,\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/376487caa98c45c7be20b251003e788b-222x300.webp 222w,\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/376487caa98c45c7be20b251003e788b-111x150.webp 111w\" sizes=\"(max-width: 319px) 100vw, 319px\" type=\"image\/webp\"><img src=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/376487caa98c45c7be20b251003e788b.jpg\" height=\"431\" width=\"319\" srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/376487caa98c45c7be20b251003e788b.jpg 319w, \/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/376487caa98c45c7be20b251003e788b-222x300.jpg 222w, \/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/376487caa98c45c7be20b251003e788b-111x150.jpg 111w\" sizes=\"(max-width: 319px) 100vw, 319px\" class=\"wp-image-45880 sp-no-webp\" alt=\"\" decoding=\"async\"  > <\/picture><figcaption class=\"wp-element-caption\">\u9130\u8fd1\u91cd\u8981\u5668\u5b98&#8211;\u98df\u9053\u9130\u8fd1\u6709\u8a31\u591a\u91cd\u8981\u5668\u5b98\uff0c\u5982\u5fc3\u81df\u3001\u80ba\u90e8\u3001\u6c23\u7ba1\u3001\u5927\u52d5\u8108\u7b49\uff0c\u82e5\u816b\u7624\u8f03\u5927\uff0c\u75c5\u4eba\u53ef\u80fd\u51fa\u73fe\u5410\u8840\u3001\u547c\u5438\u56f0\u96e3\u7b49\u3002\uff08kowalska-art@iStockphoto\uff09<\/figcaption><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-cyan-bluish-gray-color has-alpha-channel-opacity has-cyan-bluish-gray-background-color has-background is-style-wide\"\/>\n\n\n\n<p>\u76f8\u95dc\u95b2\u8b80\uff1a<a href=\"\/\/www.afterroberto.com\/%e9%a3%9f%e9%81%93%e7%99%8c%e5%be%b5%e5%85%86-%e5%90%9e%e5%9a%a5%e6%9c%89%e7%95%b0%e7%89%a9%e6%84%9f-%e9%80%b2%e9%a3%9f%e5%96%9d%e6%b0%b4%e7%96%bc%e7%97%9b-%e8%83%b8%e9%aa%a8%e5%be%8c%e4%b8%8d\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u98df\u9053\u764c3\u5fb5\u5146\uff1a\u541e\u56a5\u6709\u7570\u7269\u611f\u3001\u9032\u98df\u559d\u6c34\u75bc\u75db\u3001\u80f8\u9aa8\u5f8c\u4e0d\u9069 \u5fcc\u5403\u81d8\u5473\u71d2\u70e4\u592a\u71b1\u98df\u7269<\/a><\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e00\u534a\u60a3\u8005\u8853\u5f8c1\u81f32\u5e74\u5fa9\u767c<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">\u82e5\u98df\u9053\u764c\u6c92\u6709\u64f4\u6563\uff0c\u53ef\u4ee5\u600e\u6a23\u8655\u7406\uff1f<\/h2>\n\n\n\n<p>\u82e5\u98df\u9053\u764c\u5c6c\u4e2d\u671f\u4f46\u672a\u64f4\u6563\uff0c\u7121\u6cd5\u76f4\u63a5\u505a\u5207\u9664\u6839\u6cbb\u624b\u8853\uff0c\u6cbb\u7642\u65b9\u5f0f\u662f\u5148\u505a\u5316\u7642\u548c\u96fb\u7642\uff0c\u628a\u816b\u7624\u7e2e\u5c0f\u5f8c\uff0c\u518d\u5b89\u6392\u624b\u8853\u5207\u9664\u3002\u4e0d\u904e\uff0c\u5373\u4f7f\u505a\u4e86\u624b\u8853\uff0c\u9810\u5f8c\u4e5f\u4e0d\u592a\u7406\u60f3\uff0c\u4ecd\u6709\u8d85\u904e\u4e00\u534a\u60a3\u8005\u5728\u8853\u5f8c1\u81f32\u5e74\u5fa9\u767c\u3002<\/p>\n\n\n\n<p>\u8fd1\u5e74\uff0c\u6709\u7b2c\u4e09\u671f\u81e8\u7240\u7814\u7a76\u8b49\u660e\uff0c\u5229\u7528\u514d\u75ab\u6cbb\u7642\u70ba\u8853\u5f8c\u8f14\u52a9\u6cbb\u7642\uff0c\u5c0d\u5df2\u63a5\u53d7\u5316\u7642\u96fb\u7642\u518d\u505a\u624b\u8853\uff0c\u800c\u8853\u5f8c\u4ecd\u767c\u73fe\u6b98\u5b58\u816b\u7624\u7d30\u80de\u7684\u9c57\u72c0\u98df\u9053\u764c\u75c5\u4eba\uff0c\u80fd\u6709\u52a9\u6e1b\u4f4e\u816b\u7624\u5fa9\u767c\u53ca\u8f49\u79fb\u98a8\u96aa\u3002<\/p>\n\n\n\n<p>\u53e6\u5916\uff0c\u570b\u969b\u8207\u5167\u5730\u4ea6\u6b63\u505a\u7814\u7a76\uff0c\u6df7\u5408\u514d\u75ab\u6cbb\u7642\u85e5\u7269\u548c\u5316\u7642\u85e5\u7269\u4f5c\u65b0\u8f14\u52a9\u6cbb\u7642\uff0c\u5728\u624b\u8853\u524d\u5148\u628a\u816b\u7624\u7e2e\u5c0f\uff0c\u671f\u671b\u9019\u4e9b\u7814\u7a76\u80fd\u5e6b\u52a9\u98df\u9053\u764c\u60a3\u8005\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><picture><source srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-1024x563.webp 1024w,\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-300x165.webp 300w,\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-150x82.webp 150w,\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-768x422.webp 768w,\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882.webp 1051w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" type=\"image\/webp\"><img src=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-1024x563.jpg\" height=\"563\" width=\"1024\" srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-1024x563.jpg 1024w, \/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-300x165.jpg 300w, \/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-150x82.jpg 150w, \/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882-768x422.jpg 768w, \/\/www.afterroberto.com\/wp-content\/uploads\/2024\/01\/b5737a318b9642c9bd6c4d7634712882.jpg 1051w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" class=\"wp-image-45878 sp-no-webp\" alt=\"\" decoding=\"async\"  > <\/picture><figcaption class=\"wp-element-caption\">\uff08Dr_Microbe@iStockphoto\uff09<\/figcaption><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u514d\u75ab+\u5316\u7642\u6cbb\u665a\u671f \u63d0\u5347\u5b58\u6d3b\u7387<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">\u82e5\u98df\u9053\u764c\u5df2\u64f4\u6563\uff0c\u514d\u75ab\u6cbb\u7642\u6709\u6548\u55ce\uff1f<\/h2>\n\n\n\n<p>\u4ee5\u5f80\u5df2\u64f4\u6563\u7684\u98df\u9053\u764c\u6703\u63a1\u7528\u7d13\u7de9\u5316\u7642\u4f86\u63a7\u5236\u75c5\u60c5\uff0c\u5e38\u7528\u4e00\u7dda\u5316\u7642\u85e5\u7269\u5305\u62ec\u9806\u9251\uff08cisplatin\uff09\u548c5-\u6c1f\u5c3f\u5627\u5576\uff085-fluorouracil\uff0c\u7c21\u7a315-FU\uff09\u4f5c\u6df7\u5408\u7642\u7a0b\uff0c\u4f46\u6548\u679c\u4e0d\u592a\u7406\u60f3\uff0c\u6709\u6548\u7de9\u89e3\u7387\u7d0430%\u81f340%\uff0c\u7121\u60e1\u5316\u5b58\u6d3b\u7387\u7d044\u81f35\u500b\u6708\u3002\u82e5\u4e00\u7dda\u5316\u7642\u7121\u6548\uff0c\u4fbf\u6703\u8f49\u7528\u7b2c\u4e8c\u7dda\u5316\u7642\u85e5\u7269\uff0c\u4f8b\u5982\u7d2b\u6749\u9187\uff0c\u4f46\u6cbb\u7642\u6548\u679c\u4e5f\u4e0d\u592a\u7406\u60f3\uff0c\u4e2d\u4f4d\u5b58\u6d3b\u7387\u7d048\u81f310\u500b\u6708\u4e4b\u5167\u3002<\/p>\n\n\n\n<p>\u8fd1\u5e74\u81e8\u7240\u7814\u7a76\u8b49\u660e\uff0c\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\uff08immune checkpoint inhibitors\uff0c\u53c8\u7a31\u514d\u75ab\u6cbb\u7642\uff09\u5c0d\u8f49\u79fb\u6216\u5fa9\u767c\u6027\u98df\u9053\u9c57\u72c0\u764c\u60a3\u8005\u6709\u5e6b\u52a9\uff0c\u53ef\u4ee5\u8207\u5316\u7642\u6df7\u5408\u4f7f\u7528\u4f5c\u4e00\u7dda\u6cbb\u7642\u6216\u55ae\u7368\u4f7f\u7528\u4f5c\u4e8c\u7dda\u6cbb\u7642\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. \u4e00\u7dda\u6cbb\u7642<\/h2>\n\n\n\n<p>\u73fe\u6642\uff0c\u570b\u969b\u548c\u5167\u5730\u90fd\u6709\u7814\u7a76\u986f\u793a\uff0c\u6df7\u5408\u514d\u75ab\u6cbb\u7642\u548c\u5316\u7642\u4f7f\u7528\u5728\u8f49\u79fb\u6027\u98df\u9053\u9c57\u72c0\u764c\u60a3\u8005\uff0c\u80fd\u66f4\u6709\u6548\u63a7\u5236\u75c5\u60c5\u548c\u5ef6\u9577\u58fd\u547d\u3002\u4f8b\u5982\uff1a\u5728Keynote 590\u7814\u7a76\uff0c749\u540d\u8f49\u79fb\u6027\u665a\u671f\u98df\u9053\u764c\u60a3\u8005\u88ab\u96a8\u6a5f\u5206\u914d\u81f3\u5169\u7d44\uff0c\u4e00\u7d44\u63a5\u53d7\u5316\u7642\u548c\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5e15\u535a\u5229\u73e0\u55ae\u6297\uff08pembrolizumab\uff09\uff0c\u800c\u53e6\u4e00\u7d44\u53ea\u63a5\u53d7\u5316\u7642\u3002\u7d50\u679c\u986f\u793a\uff0c\u82e5\u75c5\u4eba\u816b\u7624\u5e36\u6709\u514d\u75ab\u6aa2\u67e5\u9edePD-L1\u967d\u6027\uff0c\u63a5\u53d7\u6df7\u5408\u6cbb\u7642\u7684\u75c5\u4eba\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u75315.5\u500b\u6708\u5347\u81f37.5\u500b\u6708\uff0c\u800c\u6574\u9ad4\u5b58\u6d3b\u671f\u4e5f\u660e\u986f\u589e\u52a0\uff0c\u75319.4\u500b\u6708\u5347\u81f313.5\u500b\u6708\u3002<\/p>\n\n\n\n<p>\u53e6\u4e00\u7814\u7a76\u662f\u57282022\u5e74\u82f1\u570b\u91ab\u5b78\u671f\u520a\u520a\u767b\u7684Checkmate 648\u7814\u7a76\u5831\u544a\uff0c\u8b49\u5be6\u5229\u7528\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u7d0d\u6b66\u5229\u5c24\u55ae\u6297\uff08nivolumab\uff09\u548c\u5316\u7642\uff0c\u6df7\u5408\u7528\u65bc\u665a\u671f\u98df\u9053\u9c57\u72c0\u764c\u60a3\u8005\uff0c\u6bd4\u8d77\u53ea\u7528\u5316\u7642\u85e5\u7269\uff0c\u80fd\u66f4\u6709\u6548\u63a7\u5236\u75c5\u60c5\uff0c\u7d04\u4e94\u6210\u75c5\u4eba\u7528\u85e5\u5f8c\u816b\u7624\u7e2e\u5c0f\uff0c\u63d0\u5347\u7121\u60e1\u5316\u5b58\u6d3b\u7387\uff0c\u4e26\u5ef6\u9577\u58fd\u547d\uff0c\u75319.1\u500b\u6708\u5347\u81f315.4\u500b\u6708\u3002<\/p>\n\n\n\n<p>\u53e6\u5916\uff0c\u5167\u5730\u4e5f\u6709\u7814\u767c\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5982\u4fe1\u8fea\u5229\u55ae\u6297\uff08sintilimab\uff09\u3001\u66ff\u96f7\u5229\u73e0\u55ae\u6297\uff08tislelizumab\uff09\u3001\u5361\u745e\u5229\u73e0\u55ae\u6297\uff08camrelizumab\uff09\u7b49\u505a\u7b2c\u4e09\u671f\u7814\u7a76\uff0c\u6548\u679c\u4e5f\u5341\u5206\u986f\u8457\uff0c\u4e26\u8207\u570b\u969b\u7814\u7a76\u6210\u679c\u8117\u5408\uff0c\u4ee4\u4eba\u9f13\u821e\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. \u4e8c\u7dda\u6cbb\u7642<\/h2>\n\n\n\n<p>\u514d\u75ab\u6cbb\u7642\u9664\u4e86\u4f5c\u4e00\u7dda\u6cbb\u7642\u4e4b\u5916\uff0c\u7814\u7a76\u4e5f\u6307\u51fa\uff0c\u55ae\u7528\u514d\u75ab\u6cbb\u7642\u4f5c\u4e8c\u7dda\u6cbb\u7642\uff0c\u6bd4\u7d2b\u6749\u9187\u5316\u7642\u66f4\u6709\u6548\u63a7\u5236\u75c5\u60c5\u548c\u5ef6\u9577\u7121\u60e1\u5316\u5b58\u6d3b\u7387\u548c\u7e3d\u5b58\u6d3b\u7387\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u652f\u67b6\u6490\u958b\u98df\u9053\u52a9\u9032\u98df<\/h2>\n\n\n\n<p>\u82e5\u98df\u9053\u764c\u5c0e\u81f4\u4e0d\u80fd\u9032\u98df\uff0c\u6709\u4ec0\u9ebc\u65b9\u6cd5\u53ef\u4ee5\u89e3\u6c7a\u9032\u98df\u554f\u984c\u5462\uff1f<\/p>\n\n\n\n<p>\u9664\u4e86\u5316\u7642\u548c\u514d\u75ab\u6cbb\u7642\uff0c\u53ef\u4ee5\u5229\u7528\u7d13\u7de9\u96fb\u7642\uff0c\u91ab\u751f\u6703\u6309\u75c5\u4eba\u9700\u8981\u6c7a\u5b9a\u6b21\u6578\uff0c\u7d0410\u81f325\u6b21\uff1b\u5916\u79d1\u91ab\u751f\u4e5f\u53ef\u4ee5\u5229\u7528\u5167\u7aba\u93e1\u653e\u5165\u98df\u9053\u652f\u67b6\uff0c\u6490\u958b\u816b\u7624\u963b\u585e\u7684\u4f4d\u7f6e\uff0c\u8b93\u60a3\u8005\u80fd\u5920\u9032\u98df\u3002<\/p>\n\n\n\n<p>\u738b\u5148\u751f\u5728\u8a3a\u75c7\u6642\u6700\u5f8c\u554f\u5230\uff0c\u4ed6\u5e74\u7d00\u6bd4\u8f03\u5927\u662f\u5426\u80fd\u5920\u6490\u5f97\u4f4f\u5404\u9805\u6cbb\u7642\uff0c\u6211\u56de\u7b54\uff1a\u300c\u76f8\u4fe1\u5e74\u7d00\u4e26\u4e0d\u662f\u6700\u5927\u554f\u984c\uff0c\u6211\u5011\u9084\u9700\u8981\u770b\u75c5\u4eba\u7684\u9ad4\u8cea\u548c\u4ee5\u5f80\u5065\u5eb7\u7d00\u9304\uff0c\u4f86\u6c7a\u5b9a\u7528\u85e5\u548c\u6cbb\u7642\u8a08\u5283\uff0c\u816b\u7624\u79d1\u91ab\u751f\u4e5f\u6703\u6309\u75c5\u4eba\u60c5\u51b5\uff0c\u8abf\u7bc0\u85e5\u7269\u7684\u5291\u91cf\uff0c\u5e0c\u671b\u85e5\u7269\u6548\u679c\u548c\u526f\u4f5c\u7528\u4e4b\u9593\u80fd\u53d6\u5e73\u8861\u3002\u300d<\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-cyan-bluish-gray-color has-alpha-channel-opacity has-cyan-bluish-gray-background-color has-background is-style-wide\"\/>\n\n\n\n<p>\u76f8\u95dc\u95b2\u8b80\uff1a<a href=\"\/\/www.afterroberto.com\/%e5%90%9e%e5%9a%a5%e5%9b%b0%e9%9b%a3-%e7%b6%93%e5%b8%b8%e6%bf%81%e8%a6%aa-%e8%90%bd%e9%8c%af%e6%a0%bc-%e4%ba%86%e8%a7%a3%e5%90%9e%e5%9a%a5%e5%8b%95%e4%bd%9c4%e9%9a%8e%e6%ae%b5-%e5%8f%8a%e6%97%a9\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u541e\u56a5\u56f0\u96e3\uff5c\u7d93\u5e38\u300c\u6fc1\u89aa\u300d\u3001\u300c\u843d\u932f\u683c\u300d\uff1f\u4e86\u89e3\u541e\u56a5\u52d5\u4f5c4\u968e\u6bb5 \u53ca\u65e9\u8655\u7406\u514d\u81f4\u5438\u5165\u6027\u80ba\u708e<\/a><\/p>\n\n\n\n<p><\/p>\n\n\n\n<h1 class=\"wp-block-heading\">\u652f\u63f4\u764c\u75c7\u60a3\u8005\u5728\u5bb6\u8b77\u7406<\/h1>\n\n\n\n<p>\u300c\u5bb6\u652f\u63f4\u300d\u793e\u5340\u7d13\u7de9\u6cbb\u7642\u61c9\u7528\u7a0b\u5f0f\uff0c\u662f\u9999\u6e2f\u5927\u5b78\u81e8\u7240\u816b\u7624\u79d1\u5c6c\u4e0b\u4e00\u500b\u9805\u76ee\u3002\u300c\u5bb6\u652f\u63f4\u300d\u6709\u300c\u52a0\u300d\u5f37\u300c\u5bb6\u300d\u5ead\u652f\u63f4\u4e4b\u610f\uff0c\u61c9\u7528\u7a0b\u5f0f\u5e0c\u671b\u80fd\u652f\u63f4\u764c\u75c7\u75c5\u4eba\u548c\u5bb6\u4eba\u5728\u5bb6\u7167\u9867\uff0c\u70ba\u4ed6\u5011\u52a0\u6dfb\u53ef\u7528\u8cc7\u6e90\uff0c\u4ee5\u6b63\u9762\u7a4d\u6975\u5fc3\u614b\u9762\u5c0d\u764c\u75c5\uff1b\u4f8b\u5982\u61c9\u7528\u7a0b\u5f0f\u5167\u300c\u8a8d\u8b58\u591a\u4e00\u9ede\u300d\u63d0\u4f9b\u764c\u75c7\u8cc7\u8a0a\u3001\u7d13\u7de9\u6cbb\u7642\u548c\u5b89\u5be7\u670d\u52d9\u7684\u8cc7\u6599\uff0c\u8b93\u75c5\u4eba\u548c\u7167\u9867\u8005\u80fd\u88dd\u5099\u81ea\u5df1\uff0c\u6709\u8db3\u5920\u77e5\u8b58\u548c\u6280\u5de7\u5728\u5bb6\u8b77\u7406\u3002\u4e0b\u8f09\u61c9\u7528\u7a0b\u5f0f\uff1a<a href=\"http:\/\/shorturl.at\/dLXZ8\" target=\"_blank\" rel=\"noreferrer noopener\">shorturl.at\/dLXZ8<\/a><\/p>\n\n\n\n<p>\u6587\uff1a\u9673\u7a4e\u6a02<\/p>\n\n\n\n<p>\uff08\u9999\u6e2f\u5927\u5b78\u81e8\u7240\u816b\u7624\u5b78\u7cfb\u81e8\u7240\u52a9\u7406\u6559\u6388\uff09<\/p>\n\n\n\n<p>\u7de8\u8f2f\uff1a\u6881\u5c0f\u73b2<\/p>\n\n\n\n<p>\u7f8e\u8853\uff1a\u8b1d\u5049\u8c6a<\/p>\n\n\n\n<p>facebook @\u660e\u5831\u526f\u520a<\/p>\n\n\n\n<p>\u660e\u5831\u5065\u5eb7\u7db2\uff1a<a href=\"\/\/www.afterroberto.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">www.afterroberto.com<\/a><\/p>\n\n\n\n<p>\u96fb\u90f5\uff1a<a>feature@mingpao.com<\/a><\/p>\n\n\n\n<p>\uff08\u672c\u7db2\u767c\u8868\u7684\u4f5c\u54c1\u82e5\u63d0\u51fa\u6279\u8a55\uff0c\u65e8\u5728\u6307\u51fa\u76f8\u95dc\u5236\u5ea6\u3001\u653f\u7b56\u6216\u63aa\u65bd\u5b58\u5728\u932f\u8aa4\u6216\u7f3a\u9ede\uff0c\u76ee\u7684\u662f\u4fc3\u4f7f\u77ef\u6b63\u6216\u6d88\u9664\u9019\u4e9b\u932f\u8aa4\u6216\u7f3a\u9ede\uff0c\u5faa\u5408\u6cd5\u9014\u5f91\u4e88\u4ee5\u6539\u5584\uff0c\u7d55\u7121\u610f\u5716\u717d\u52d5\u4ed6\u4eba\u5c0d\u653f\u5e9c\u6216\u5176\u4ed6\u793e\u7fa4\u7522\u751f\u618e\u6068\u3001\u4e0d\u6eff\u6216\u6575\u610f\u3002\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u660e\u5831\u5c08\u8a0a\u3011\u6839\u64da\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc3\u7684\u6578\u64da\u986f\u793a\uff0c\u9999\u6e2f\u904e\u53bb10\u5e74\uff0c\u6bcf\u5e74\u5e73\u5747\u7d04\u6709410\u5b97\u98df\u9053\u764c\u65b0\u75c7\uff0c\u903e310\u4eba\u6b7b\u65bc\u98df\u9053\u764c\u3002\u98df\u9053\u662f\u4e00\u500b\u7ba1\u72c0\u5668\u5b98\uff0c\u9023\u63a5\u54bd\u5589\u548c\u80c3\u90e8\uff0c\u9577\u7d0425\u81f330\u5398\u7c73\u3002\u98df\u9053\u672c\u8eab\u6c92\u6709\u6d88\u5316\u98df\u7269\u7684\u529f\u80fd\uff0c\u53ea\u662f\u901a\u904e\u8815\u52d5\u5c07\u98df\u7269\u9001\u5230\u80c3\u90e8\u6d88\u5316\u3002\u98df\u9053\u764c\u60a3\u8005\u5e38\u898b\u75c7\u72c0\u662f\u541e\u56a5\u56f0\u96e3\uff0c\u4f46\u60a3\u8005\u8a31\u591a\u6642\u6703\u8abf\u7bc0\u9032\u98df\u7fd2\u6163\uff0c\u5982\u54ac\u788e\u4e00\u9ede\u624d\u541e\u56a5\uff0c\u5ffd\u7565\u6cbb\u7642\uff0c\u56e0\u800c\u5c0e\u81f4\u75c5\u60c5\u60e1\u5316\u3002\uff08\u7de8\u6309\uff1a\u98df\u9053\u9130\u8fd1\u6709\u8a31\u591a\u91cd\u8981\u5668\u5b98\uff0c\u5982\u5fc3\u81df\u3001\u80ba\u90e8\u3001\u6c23\u7ba1\u3001\u5927\u52d5\u8108\u7b49\uff0c\u82e5\u816b\u7624\u8f03\u5927\uff0c\u75c5\u4eba\u6709\u53ef\u80fd\u51fa\u73fe\u5410\u8840\u3001\u547c\u5438\u56f0\u96e3\u7b49\u3002\u82e5\u98df\u9053\u764c\u6c92\u6709\u6216\u5df2\u64f4\u6563\uff0c\u5728\u6cbb\u7642\u53c8\u6709\u4ec0\u9ebc\u4e0d\u540c\uff1f\u514d\u75ab\u6cbb\u7642\u6709\u6548\u55ce\uff1f\uff09 \u98df\u9053\u764c\u5e38\u898b\u75c7\u72c0\u541e\u56a5\u56f0\u96e3 \u9130\u8fd1\u5fc3\u80ba\u6c23\u7ba1\u6216\u5410\u8840\u547c\u5438\u56f0\u96e3 \u738b\u5148\u751f\uff0c74\u6b72\uff0c3\u500b\u6708\u524d\u958b\u59cb\u611f\u5230\u541e\u56a5\u56f0\u96e3\uff0c\u5411\u5916\u79d1\u91ab\u751f\u6c42\u8a3a\uff0c\u80c3\u93e1\u767c\u73fe\u98df\u9053\u6709\u816b\u7624\uff0c\u7d44\u7e54\u5316\u9a57\u78ba\u8a3a\u9c57\u72c0\u98df\u9053\u764c\uff0c\u8f49\u4ecb\u4f86\u5230\u816b\u7624\u79d1\u3002\u6211\u5efa\u8b70\u4ed6\u5148\u505a\u6b63\u96fb\u5b50\u6383\u63cf\uff0c\u4ee5\u80af\u5b9a\u816b\u7624\u6709\u5426\u64f4\u6563\u81f3\u5176\u4ed6\u5730\u65b9\uff0c\u624d\u4f5c\u4e0b\u4e00\u6b65\u7642\u7a0b\u8a08\u5283\u3002\u9019\u4e5f\u5e36\u51fa\u4e86\u4ee5\u4e0b\u554f\u984c\uff1a \u98df\u9053\u764c\u60a3\u8005\u591a\u65bc\u521d\u671f\u611f\u5230\u541e\u56a5\u56f0\u96e3\uff0c\u4f46\u60a3\u8005\u8a31\u591a\u6642\u5019\u6703\u4e0d\u81ea\u89ba\u5730\u6539\u8b8a\u9032\u98df\u7fd2\u6163\uff0c\u4f8b\u5982\u54ac\u788e\u4e00\u9ede\u624d\u541e\u56a5\uff0c\u6216\u9032\u98df\u8cea\u5730\u8f03\u8edf\u7684\u98df\u7269\uff0c\u5ffd\u7565\u6cbb\u7642\uff0c\u56e0\u800c\u5c0e\u81f4\u75c5\u60c5\u60e1\u5316\u3002\u60a3\u8005\u9032\u98df\u6642\u4e5f\u53ef\u80fd\u611f\u5230\u80f8\u90e8\u4e0d\u9069\u6216\u75bc\u75db\uff0c\u751a\u81f3\u5614\u5410\uff1b\u7531\u65bc\u60a3\u8005\u7121\u6cd5\u6b63\u5e38\u9032\u98df\uff0c\u6703\u4ee4\u9ad4\u91cd\u4e0b\u964d\u548c\u6d88\u7626\u3002\u98df\u9053\u9130\u8fd1\u6709\u8a31\u591a\u91cd\u8981\u5668\u5b98\uff0c\u5982\u5fc3\u81df\u3001\u80ba\u90e8\u3001\u6c23\u7ba1\u3001\u5927\u52d5\u8108\u7b49\uff0c\u82e5\u816b\u7624\u8f03\u5927\uff0c\u75c5\u4eba\u6709\u53ef\u80fd\u51fa\u73fe\u5410\u8840\u3001\u547c\u5438\u56f0\u96e3\u7b49\u3002 \u76f8\u95dc\u95b2\u8b80\uff1a\u98df\u9053\u764c3\u5fb5\u5146\uff1a\u541e\u56a5\u6709\u7570\u7269\u611f\u3001\u9032\u98df\u559d\u6c34\u75bc\u75db\u3001\u80f8\u9aa8\u5f8c\u4e0d\u9069 \u5fcc\u5403\u81d8\u5473\u71d2\u70e4\u592a\u71b1\u98df\u7269 \u4e00\u534a\u60a3\u8005\u8853\u5f8c1\u81f32\u5e74\u5fa9\u767c \u82e5\u98df\u9053\u764c\u6c92\u6709\u64f4\u6563\uff0c\u53ef\u4ee5\u600e\u6a23\u8655\u7406\uff1f \u82e5\u98df\u9053\u764c\u5c6c\u4e2d\u671f\u4f46\u672a\u64f4\u6563\uff0c\u7121\u6cd5\u76f4\u63a5\u505a\u5207\u9664\u6839\u6cbb\u624b\u8853\uff0c\u6cbb\u7642\u65b9\u5f0f\u662f\u5148\u505a\u5316\u7642\u548c\u96fb\u7642\uff0c\u628a\u816b\u7624\u7e2e\u5c0f\u5f8c\uff0c\u518d\u5b89\u6392\u624b\u8853\u5207\u9664\u3002\u4e0d\u904e\uff0c\u5373\u4f7f\u505a\u4e86\u624b\u8853\uff0c\u9810\u5f8c\u4e5f\u4e0d\u592a\u7406\u60f3\uff0c\u4ecd\u6709\u8d85\u904e\u4e00\u534a\u60a3\u8005\u5728\u8853\u5f8c1\u81f32\u5e74\u5fa9\u767c\u3002 \u8fd1\u5e74\uff0c\u6709\u7b2c\u4e09\u671f\u81e8\u7240\u7814\u7a76\u8b49\u660e\uff0c\u5229\u7528\u514d\u75ab\u6cbb\u7642\u70ba\u8853\u5f8c\u8f14\u52a9\u6cbb\u7642\uff0c\u5c0d\u5df2\u63a5\u53d7\u5316\u7642\u96fb\u7642\u518d\u505a\u624b\u8853\uff0c\u800c\u8853\u5f8c\u4ecd\u767c\u73fe\u6b98\u5b58\u816b\u7624\u7d30\u80de\u7684\u9c57\u72c0\u98df\u9053\u764c\u75c5\u4eba\uff0c\u80fd\u6709\u52a9\u6e1b\u4f4e\u816b\u7624\u5fa9\u767c\u53ca\u8f49\u79fb\u98a8\u96aa\u3002 \u53e6\u5916\uff0c\u570b\u969b\u8207\u5167\u5730\u4ea6\u6b63\u505a\u7814\u7a76\uff0c\u6df7\u5408\u514d\u75ab\u6cbb\u7642\u85e5\u7269\u548c\u5316\u7642\u85e5\u7269\u4f5c\u65b0\u8f14\u52a9\u6cbb\u7642\uff0c\u5728\u624b\u8853\u524d\u5148\u628a\u816b\u7624\u7e2e\u5c0f\uff0c\u671f\u671b\u9019\u4e9b\u7814\u7a76\u80fd\u5e6b\u52a9\u98df\u9053\u764c\u60a3\u8005\u3002 \u514d\u75ab+\u5316\u7642\u6cbb\u665a\u671f \u63d0\u5347\u5b58\u6d3b\u7387 \u82e5\u98df\u9053\u764c\u5df2\u64f4\u6563\uff0c\u514d\u75ab\u6cbb\u7642\u6709\u6548\u55ce\uff1f \u4ee5\u5f80\u5df2\u64f4\u6563\u7684\u98df\u9053\u764c\u6703\u63a1\u7528\u7d13\u7de9\u5316\u7642\u4f86\u63a7\u5236\u75c5\u60c5\uff0c\u5e38\u7528\u4e00\u7dda\u5316\u7642\u85e5\u7269\u5305\u62ec\u9806\u9251\uff08cisplatin\uff09\u548c5-\u6c1f\u5c3f\u5627\u5576\uff085-fluorouracil\uff0c\u7c21\u7a315-FU\uff09\u4f5c\u6df7\u5408\u7642\u7a0b\uff0c\u4f46\u6548\u679c\u4e0d\u592a\u7406\u60f3\uff0c\u6709\u6548\u7de9\u89e3\u7387\u7d0430%\u81f340%\uff0c\u7121\u60e1\u5316\u5b58\u6d3b\u7387\u7d044\u81f35\u500b\u6708\u3002\u82e5\u4e00\u7dda\u5316\u7642\u7121\u6548\uff0c\u4fbf\u6703\u8f49\u7528\u7b2c\u4e8c\u7dda\u5316\u7642\u85e5\u7269\uff0c\u4f8b\u5982\u7d2b\u6749\u9187\uff0c\u4f46\u6cbb\u7642\u6548\u679c\u4e5f\u4e0d\u592a\u7406\u60f3\uff0c\u4e2d\u4f4d\u5b58\u6d3b\u7387\u7d048\u81f310\u500b\u6708\u4e4b\u5167\u3002 \u8fd1\u5e74\u81e8\u7240\u7814\u7a76\u8b49\u660e\uff0c\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\uff08immune checkpoint inhibitors\uff0c\u53c8\u7a31\u514d\u75ab\u6cbb\u7642\uff09\u5c0d\u8f49\u79fb\u6216\u5fa9\u767c\u6027\u98df\u9053\u9c57\u72c0\u764c\u60a3\u8005\u6709\u5e6b\u52a9\uff0c\u53ef\u4ee5\u8207\u5316\u7642\u6df7\u5408\u4f7f\u7528\u4f5c\u4e00\u7dda\u6cbb\u7642\u6216\u55ae\u7368\u4f7f\u7528\u4f5c\u4e8c\u7dda\u6cbb\u7642\u3002 1. \u4e00\u7dda\u6cbb\u7642 \u73fe\u6642\uff0c\u570b\u969b\u548c\u5167\u5730\u90fd\u6709\u7814\u7a76\u986f\u793a\uff0c\u6df7\u5408\u514d\u75ab\u6cbb\u7642\u548c\u5316\u7642\u4f7f\u7528\u5728\u8f49\u79fb\u6027\u98df\u9053\u9c57\u72c0\u764c\u60a3\u8005\uff0c\u80fd\u66f4\u6709\u6548\u63a7\u5236\u75c5\u60c5\u548c\u5ef6\u9577\u58fd\u547d\u3002\u4f8b\u5982\uff1a\u5728Keynote 590\u7814\u7a76\uff0c749\u540d\u8f49\u79fb\u6027\u665a\u671f\u98df\u9053\u764c\u60a3\u8005\u88ab\u96a8\u6a5f\u5206\u914d\u81f3\u5169\u7d44\uff0c\u4e00\u7d44\u63a5\u53d7\u5316\u7642\u548c\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5e15\u535a\u5229\u73e0\u55ae\u6297\uff08pembrolizumab\uff09\uff0c\u800c\u53e6\u4e00\u7d44\u53ea\u63a5\u53d7\u5316\u7642\u3002\u7d50\u679c\u986f\u793a\uff0c\u82e5\u75c5\u4eba\u816b\u7624\u5e36\u6709\u514d\u75ab\u6aa2\u67e5\u9edePD-L1\u967d\u6027\uff0c\u63a5\u53d7\u6df7\u5408\u6cbb\u7642\u7684\u75c5\u4eba\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u75315.5\u500b\u6708\u5347\u81f37.5\u500b\u6708\uff0c\u800c\u6574\u9ad4\u5b58\u6d3b\u671f\u4e5f\u660e\u986f\u589e\u52a0\uff0c\u75319.4\u500b\u6708\u5347\u81f313.5\u500b\u6708\u3002 \u53e6\u4e00\u7814\u7a76\u662f\u57282022\u5e74\u82f1\u570b\u91ab\u5b78\u671f\u520a\u520a\u767b\u7684Checkmate 648\u7814\u7a76\u5831\u544a\uff0c\u8b49\u5be6\u5229\u7528\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u7d0d\u6b66\u5229\u5c24\u55ae\u6297\uff08nivolumab\uff09\u548c\u5316\u7642\uff0c\u6df7\u5408\u7528\u65bc\u665a\u671f\u98df\u9053\u9c57\u72c0\u764c\u60a3\u8005\uff0c\u6bd4\u8d77\u53ea\u7528\u5316\u7642\u85e5\u7269\uff0c\u80fd\u66f4\u6709\u6548\u63a7\u5236\u75c5\u60c5\uff0c\u7d04\u4e94\u6210\u75c5\u4eba\u7528\u85e5\u5f8c\u816b\u7624\u7e2e\u5c0f\uff0c\u63d0\u5347\u7121\u60e1\u5316\u5b58\u6d3b\u7387\uff0c\u4e26\u5ef6\u9577\u58fd\u547d\uff0c\u75319.1\u500b\u6708\u5347\u81f315.4\u500b\u6708\u3002 \u53e6\u5916\uff0c\u5167\u5730\u4e5f\u6709\u7814\u767c\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5982\u4fe1\u8fea\u5229\u55ae\u6297\uff08sintilimab\uff09\u3001\u66ff\u96f7\u5229\u73e0\u55ae\u6297\uff08tislelizumab\uff09\u3001\u5361\u745e\u5229\u73e0\u55ae\u6297\uff08camrelizumab\uff09\u7b49\u505a\u7b2c\u4e09\u671f\u7814\u7a76\uff0c\u6548\u679c\u4e5f\u5341\u5206\u986f\u8457\uff0c\u4e26\u8207\u570b\u969b\u7814\u7a76\u6210\u679c\u8117\u5408\uff0c\u4ee4\u4eba\u9f13\u821e\u3002 2. \u4e8c\u7dda\u6cbb\u7642 \u514d\u75ab\u6cbb\u7642\u9664\u4e86\u4f5c\u4e00\u7dda\u6cbb\u7642\u4e4b\u5916\uff0c\u7814\u7a76\u4e5f\u6307\u51fa\uff0c\u55ae\u7528\u514d\u75ab\u6cbb\u7642\u4f5c\u4e8c\u7dda\u6cbb\u7642\uff0c\u6bd4\u7d2b\u6749\u9187\u5316\u7642\u66f4\u6709\u6548\u63a7\u5236\u75c5\u60c5\u548c\u5ef6\u9577\u7121\u60e1\u5316\u5b58\u6d3b\u7387\u548c\u7e3d\u5b58\u6d3b\u7387\u3002 \u652f\u67b6\u6490\u958b\u98df\u9053\u52a9\u9032\u98df \u82e5\u98df\u9053\u764c\u5c0e\u81f4\u4e0d\u80fd\u9032\u98df\uff0c\u6709\u4ec0\u9ebc\u65b9\u6cd5\u53ef\u4ee5\u89e3\u6c7a\u9032\u98df\u554f\u984c\u5462\uff1f \u9664\u4e86\u5316\u7642\u548c\u514d\u75ab\u6cbb\u7642\uff0c\u53ef\u4ee5\u5229\u7528\u7d13\u7de9\u96fb\u7642\uff0c\u91ab\u751f\u6703\u6309\u75c5\u4eba\u9700\u8981\u6c7a\u5b9a\u6b21\u6578\uff0c\u7d0410\u81f325\u6b21\uff1b\u5916\u79d1\u91ab\u751f\u4e5f\u53ef\u4ee5\u5229\u7528\u5167\u7aba\u93e1\u653e\u5165\u98df\u9053\u652f\u67b6\uff0c\u6490\u958b\u816b\u7624\u963b\u585e\u7684\u4f4d\u7f6e\uff0c\u8b93\u60a3\u8005\u80fd\u5920\u9032\u98df\u3002 \u738b\u5148\u751f\u5728\u8a3a\u75c7\u6642\u6700\u5f8c\u554f\u5230\uff0c\u4ed6\u5e74\u7d00\u6bd4\u8f03\u5927\u662f\u5426\u80fd\u5920\u6490\u5f97\u4f4f\u5404\u9805\u6cbb\u7642\uff0c\u6211\u56de\u7b54\uff1a\u300c\u76f8\u4fe1\u5e74\u7d00\u4e26\u4e0d\u662f\u6700\u5927\u554f\u984c\uff0c\u6211\u5011\u9084\u9700\u8981\u770b\u75c5\u4eba\u7684\u9ad4\u8cea\u548c\u4ee5\u5f80\u5065\u5eb7\u7d00\u9304\uff0c\u4f86\u6c7a\u5b9a\u7528\u85e5\u548c\u6cbb\u7642\u8a08\u5283\uff0c\u816b\u7624\u79d1\u91ab\u751f\u4e5f\u6703\u6309\u75c5\u4eba\u60c5\u51b5\uff0c\u8abf\u7bc0\u85e5\u7269\u7684\u5291\u91cf\uff0c\u5e0c\u671b\u85e5\u7269\u6548\u679c\u548c\u526f\u4f5c\u7528\u4e4b\u9593\u80fd\u53d6\u5e73\u8861\u3002\u300d \u76f8\u95dc\u95b2\u8b80\uff1a\u541e\u56a5\u56f0\u96e3\uff5c\u7d93\u5e38\u300c\u6fc1\u89aa\u300d\u3001\u300c\u843d\u932f\u683c\u300d\uff1f\u4e86\u89e3\u541e\u56a5\u52d5\u4f5c4\u968e\u6bb5 \u53ca\u65e9\u8655\u7406\u514d\u81f4\u5438\u5165\u6027\u80ba\u708e \u652f\u63f4\u764c\u75c7\u60a3\u8005\u5728\u5bb6\u8b77\u7406 \u300c\u5bb6\u652f\u63f4\u300d\u793e\u5340\u7d13\u7de9\u6cbb\u7642\u61c9\u7528\u7a0b\u5f0f\uff0c\u662f\u9999\u6e2f\u5927\u5b78\u81e8\u7240\u816b\u7624\u79d1\u5c6c\u4e0b\u4e00\u500b\u9805\u76ee\u3002\u300c\u5bb6\u652f\u63f4\u300d\u6709\u300c\u52a0\u300d\u5f37\u300c\u5bb6\u300d\u5ead\u652f\u63f4\u4e4b\u610f\uff0c\u61c9\u7528\u7a0b\u5f0f\u5e0c\u671b\u80fd\u652f\u63f4\u764c\u75c7\u75c5\u4eba\u548c\u5bb6\u4eba\u5728\u5bb6\u7167\u9867\uff0c\u70ba\u4ed6\u5011\u52a0\u6dfb\u53ef\u7528\u8cc7\u6e90\uff0c\u4ee5\u6b63\u9762\u7a4d\u6975\u5fc3\u614b\u9762\u5c0d\u764c\u75c5\uff1b\u4f8b\u5982\u61c9\u7528\u7a0b\u5f0f\u5167\u300c\u8a8d\u8b58\u591a\u4e00\u9ede\u300d\u63d0\u4f9b\u764c\u75c7\u8cc7\u8a0a\u3001\u7d13\u7de9\u6cbb\u7642\u548c\u5b89\u5be7\u670d\u52d9\u7684\u8cc7\u6599\uff0c\u8b93\u75c5\u4eba\u548c\u7167\u9867\u8005\u80fd\u88dd\u5099\u81ea\u5df1\uff0c\u6709\u8db3\u5920\u77e5\u8b58\u548c\u6280\u5de7\u5728\u5bb6\u8b77\u7406\u3002\u4e0b\u8f09\u61c9\u7528\u7a0b\u5f0f\uff1ashorturl.at\/dLXZ8 \u6587\uff1a\u9673\u7a4e\u6a02 \uff08\u9999\u6e2f\u5927\u5b78\u81e8\u7240\u816b\u7624\u5b78\u7cfb\u81e8\u7240\u52a9\u7406\u6559\u6388\uff09 \u7de8\u8f2f\uff1a\u6881\u5c0f\u73b2 \u7f8e\u8853\uff1a\u8b1d\u5049\u8c6a facebook @\u660e\u5831\u526f\u520a \u660e\u5831\u5065\u5eb7\u7db2\uff1awww.afterroberto.com \u96fb\u90f5\uff1afeature@mingpao.com \uff08\u672c\u7db2\u767c\u8868\u7684\u4f5c\u54c1\u82e5\u63d0\u51fa\u6279\u8a55\uff0c\u65e8\u5728\u6307\u51fa\u76f8\u95dc\u5236\u5ea6\u3001\u653f\u7b56\u6216\u63aa\u65bd\u5b58\u5728\u932f\u8aa4\u6216\u7f3a\u9ede\uff0c\u76ee\u7684\u662f\u4fc3\u4f7f\u77ef\u6b63\u6216\u6d88\u9664\u9019\u4e9b\u932f\u8aa4\u6216\u7f3a\u9ede\uff0c\u5faa\u5408\u6cd5\u9014\u5f91\u4e88\u4ee5\u6539\u5584\uff0c\u7d55\u7121\u610f\u5716\u717d\u52d5\u4ed6\u4eba\u5c0d\u653f\u5e9c\u6216\u5176\u4ed6\u793e\u7fa4\u7522\u751f\u618e\u6068\u3001\u4e0d\u6eff\u6216\u6575\u610f\u3002\uff09<\/p>\n","protected":false},"author":33,"featured_media":45886,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"rank_math_lock_modified_date":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[7],"tags":[389,558],"class_list":["post-45877","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-7","tag-389","tag-558"],"publishpress_future_action":{"enabled":false,"date":"2026-11-16 05:24:52","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/posts\/45877"}],"collection":[{"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/users\/33"}],"replies":[{"embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/comments?post=45877"}],"version-history":[{"count":0,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/posts\/45877\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/media\/45886"}],"wp:attachment":[{"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/media?parent=45877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/categories?post=45877"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/tags?post=45877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}