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30%\u60a3\u8005\u6709\u9280\u5c51\u75c5\u95dc\u7bc0\u708e<\/p>\n

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\u6587\uff1a\u4faf\u921e\u7fd4\uff08\u76ae\u819a\u79d1\u5c08\u79d1\u91ab\u751f\uff09<\/p>\n

\u7de8\u8f2f\uff1a\u738b\u7fe0\u9e97<\/p>\n

https:\/\/health2.mingpao.com\/ftp\/Health2\/20170529\/news\/_29ygz.jpg\u76ae\u819a\u7d30\u80de\u7570\u5e38\u2014\u2014\u9280\u5c51\u75c5\u4eba\u56e0\u70ba\u76ae\u819a\u7d30\u80de\u7570\u5e38\u6d3b\u8e8d\uff0c\u76ae\u819a\u66f4\u65b0\u5468\u671f\u6bd4\u6b63\u5e38\u5feb\uff0c\u4ee4\u76ae\u819a\u51fa\u73fe\u767c\u708e\u3001\u6591\u584a\u3001\u7d05\u816b\u548c\u75d5\u7662\u3002\uff08\u5716\uff1achampja@iStockphoto\uff0c\u76f8\u4e2d\u4eba\u8ddf\u672c\u6587\u75c5\u4f8b\u7121\u95dc\uff09;https:\/\/health2.mingpao.com\/ftp\/Health2\/20170529\/news\/_29YG004_.jpg\u9280\u5c51\u75c5\u2014\u2014\u9280\u5c51\u75c5\u60a3\u8005\u76ae\u819a\u51fa\u73fe\u7c97\u7cd9\u7d05\u8272\u4e18\u75b9\u6216\u73ed\u584a\uff0c\u8868\u9762\u6709\u5f88\u591a\u9280\u767d\u8272\u9c57\u5c51\uff0c\u6545\u7a31\u70ba\u9280\u5c51\u75c5\u3002\uff08\u5716\ufe55PAULandLARA@iStockphoto\uff09;<\/inline><\/p>\n","protected":false},"excerpt":{"rendered":"

【明報專訊】香港每100個人便有一人患有銀屑病（Psoriasis，又稱牛皮癬）。30歲及60歲前後是發病高峰期，當中不少是適齡懷孕的女性，患病不但影響皮膚外觀，導致情緒低落，病人往往因擔心病情惡化而不敢懷孕。<\/p>\n

王女士因為懷孕，令銀屑病惡化成膿疱型銀屑病，手指長滿膿疱；分娩後接受生物製劑治療，病情很快得到控制，她形容那份喜悅跟小孩出生不相伯仲！<\/p>\n

36歲的王女士是一名記者，即將迎接第三個小朋友的來臨。然而她是銀屑病患者，之前兩次懷孕已經有過病變的現象，今次亦不例外。懷孕前的她一直患有銀屑病，大多出現於身體的局部位置，如手肘、膝蓋、臀部，口服藥物和藥膏一般都能控制病情。但當她懷孕時，銀屑病會轉化成膿疱型銀屑病，手指長滿膿疱，更出現銀屑病造成的關節炎徵狀。奈何工作需要，加上懷孕不能亂服藥，她只能硬着頭皮，忍着不適地繼續工作，鍵盤往往滿佈膿疱破裂流出的鮮血。<\/p>\n

三大皮膚病 懷孕、壓力可觸發<\/p>\n

銀屑病並非專攻孕婦，而是現今社會最常見的三大皮膚病之一。病人局部或全部的皮膚表面會出現粗糙紅色的丘疹或斑塊，因為表面有多層銀白色的鱗屑，故稱銀屑病。雖然銀屑病的成因仍然未明，但家族史、先天基因問題、免疫系統疾病和環境變化，都可能導致銀屑病的發生。<\/p>\n

銀屑病不是傳染病，是自身免疫力系統出現了問題，過多白血球、多角形細胞和免疫力分泌物都會刺激T細胞釋放出腫瘤壞死因子（Tumor Necrosis Factor，TNF），使皮膚細胞變得過度活躍而出現異常，導致皮膚周期比正常快。正常人的皮膚由初生細胞增生至脫落約需一個月，但銀屑病人只須5至7天，同時皮膚的血液供應也會改變，令皮膚出現發炎及斑塊、紅腫或痕癢等現象。懷孕、壓力和運動後創傷，皆有可能觸發銀屑病或使病情加劇。<\/p>\n

30%患者有銀屑病關節炎<\/p>\n

除了引致皮膚發炎和紅腫，銀屑病更會導致銀屑病關節炎，外國有研究指出，高達三成銀屑病人最終會發展出銀屑病關節炎。病人最常見於膝蓋疼痛、關節僵硬，嚴重的更會變得活動困難。此外，頭皮和指甲的病徵較常被銀屑病人忽略，但往往會為社交生活帶來影響。曾經有一名空姐病人，明明不是煙民，手指甲卻無故變黃，由於工作需要，只能以指甲油遮蓋；頭皮問題也愈來愈嚴重，由於公司制服較深色，頭皮大量跌落於肩膀令她十分尷尬，不但變得害怕上班，有時連朋友聚會也不願意出席。直至手腳相繼出現病徵時求醫，才得知自己患有銀屑病。<\/p>\n

雖然銀屑病沒有生命的威脅，但它影響皮膚外觀，令病人感到尷尬、失去自信和情緒低落，更會影響身體各部分，較易出現三高、腎病甚至癌症，有研究更指銀屑病影響病人生活質素與癌症病人相似，可想而知患者承受的身心負擔的確不少。<\/p>\n

目前，銀屑病不能根治且會復發，治療目的是控制病情，讓病人回復正常的生活質素。傳統療法包括外用藥物治療、光學治療和系統性藥物治療。外用藥物治療主要為含焦油類或類固醇，以及維他命D衍生物，能抑制表皮細胞分裂，但功效不算十分顯著，而且長期使用類固醇，可引致皮膚萎縮、變薄或長出細毛等副作用。光學治療則是透過大劑量紫外線照射皮膚以減輕病情，但同時會令皮膚變得乾燥和增加皮膚癌的風險。<\/p>\n

對付病情中等或嚴重的銀屑病，系統性藥物治療是較為常用的療法，能抑制免疫系統。傳統藥物包括甲氨蝶呤（Methotrexate, MTX）和環孢素（Cyclosporin A）和維他命A酸藥物，但維他命A酸效用有限，副作用也不少，系統性藥物或會產生破壞肝臟和腎臟的副作用。對此，生物製劑療法專門針對出現系統變異的銀屑病患者，可說一個嶄新的治療概念，能大大減少傳統藥物副作用的同時，又有相同或更理想療效。<\/p>\n

生物製劑雖然較昂貴，但能迅速有效控制病情，而且減少系統性傳統藥物的副作用，大大提高病人的生活質素，能抑制免疫系統，減低角化的過程。皮膚科醫生一般會小心檢查，及選擇合適的病人，以免出現如肺癆或肝炎等不必要的副作用<\/p>\n

新療法助降心血管病風險<\/p>\n

此外，近年醫學界證實銀屑病人患心血管病的風險較高。今年初在《美國皮膚醫學會期刊》發表的一項研究發現，生物製劑療法有助保護或改善心血管問題。很少人知道的是，心血管疾病是與銀屑病相聯的代謝綜合症，銀屑病人比正常人患心血管疾病的風險都要高。該研究找來分別服用甲氨蝶呤和生物製劑的銀屑病人，觀察後發現服用生物製劑的病人，其心血管疾病風險比服用甲氨蝶呤低45%，是不少銀屑病人的福音。<\/p>\n

王女士分娩後，也接受了生物製劑治療，病情很快得到控制，兩星期後關節已活動自如；治療一個月後，皮膚大為好轉，她形容那份喜悅跟小孩出生可謂不相伯仲呢！<\/p>\n

文：侯鈞翔（皮膚科專科醫生）<\/p>\n

編輯：王翠麗<\/p>\n

https:\/\/health2.mingpao.com\/ftp\/Health2\/20170529\/news\/_29ygz.jpg皮膚細胞異常——銀屑病人因為皮膚細胞異常活躍，皮膚更新周期比正常快，令皮膚出現發炎、斑塊、紅腫和痕癢。（圖：champja@iStockphoto，相中人跟本文病例無關）;https:\/\/health2.mingpao.com\/ftp\/Health2\/20170529\/news\/_29YG004_.jpg銀屑病——銀屑病患者皮膚出現粗糙紅色丘疹或班塊，表面有很多銀白色鱗屑，故稱為銀屑病。（圖﹕PAULandLARA@iStockphoto）;<\/inline><\/p>\n","protected":false},"author":2,"featured_media":4542,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"rank_math_lock_modified_date":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[3],"tags":[827,170,169],"class_list":["post-4544","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-3","tag-827","tag-170","tag-169"],"publishpress_future_action":{"enabled":false,"date":"2026-11-16 11:32:04","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/posts\/4544"}],"collection":[{"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/comments?post=4544"}],"version-history":[{"count":0,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/posts\/4544\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/media\/4542"}],"wp:attachment":[{"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/media?parent=4544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/categories?post=4544"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.afterroberto.com\/wp-json\/wp\/v2\/tags?post=4544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}