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\u3010\u660e\u5831\u5c08\u8a0a\u301155\u6b72\u7684\u9673\u5148\u751f\uff0c10\u5e74\u524d\u78ba\u8a3a\u9ad8\u6bd2\u6027\u7684\u7030\u6f2b\u5927B\u7d30\u80de\u6dcb\u5df4\u764c<\/a>\uff0c\u91ab\u751f\u8655\u65b9\u6a19\u9776\u85e5\u7269\u5229\u59a5\u6614\u55ae\u6297\uff08rituximab\uff09\u52a0\u591a\u7a2e\u5316\u7642\u85e5\u7269\uff0c\u7642\u6548\u7406\u60f3\u3002\u9673\u5148\u751f\u8fd1\u65e5\u8eab\u9ad4\u4e0d\u9069\u3001\u98df\u617e\u4e0d\u632f\uff0c\u4e26\u6709\u4f4e\u71d2\u3002\u6b63\u96fb\u5b50\u96fb\u8166\u6383\u63cf\u986f\u793a\u8179\u8154\u6dcb\u5df4\u7d50\u816b\u5927\uff0c\u6d3b\u7d44\u7e54\u6aa2\u67e5\u78ba\u8a3a\u6dcb\u5df4\u764c\u5fa9\u767c\uff0c\u5e78\u800c\u9aa8\u9ad3\u672a\u53d7\u5f71\u97ff\u3002\u9673\u5148\u751f\u63a5\u53d7\u5229\u59a5\u6614\u52a0\u5316\u7642\uff0c\u75c5\u60c5\u518d\u5ea6\u53d7\u63a7\uff0c\u4f46\u4f30\u8a08\u5fa9\u767c\u6a5f\u7387\u4ecd\u9ad8\u3002\u9aa8\u9ad3\u672a\u898b\u764c\u7d30\u80de\uff0c\u4ed6\u53ef\u8003\u616e\u63a5\u53d7\u81ea\u9ad4\u5468\u908a\u8840\u5e79\u7d30\u80de\u79fb\u690d\uff08autologous peripheral blood stem cell transplant\uff09\uff0c\u964d\u4f4e\u6dcb\u5df4\u764c\u5fa9\u767c\u6a5f\u7387\u3002<\/p>\n

\"\u6dcb\u5df4\u764c\u662f\u672c\u6e2f\u5341\u5927\u764c\u75c7\u4e4b\u4e00\u3002\" <\/picture>
\u6dcb\u5df4\u764c\u662f\u672c\u6e2f\u5341\u5927\u764c\u75c7\u4e4b\u4e00\u3002<\/figcaption><\/figure>\n

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\u81ea\u9ad4\u5468\u908a\u8840\u5e79\u7d30\u80de\u79fb\u690d\u624b\u8853 \u6cbb\u7642\u6dcb\u5df4\u764c\u53ca\u9aa8\u9ad3\u764c\u70ba\u4e3b<\/strong><\/h2>\n

\u81ea\u9ad4\u5468\u908a\u8840\u5e79\u7d30\u80de\u79fb\u690d\u624b\u8853\uff0c\u591a\u7528\u4f5c\u6cbb\u7642\u6dcb\u5df4\u764c\u53ca\u9aa8\u9ad3\u764c<\/a>\uff0c\u7642\u6548\u7406\u60f3\u3002\u6709\u5225\u65bc\u7570\u9ad4\u8840\u5e79\u7d30\u80de\u79fb\u690d\uff08allogeneic blood stem cell transplant\uff09\uff0c\u81ea\u9ad4\u79fb\u690d\u5229\u7528\u75c5\u8005\u672c\u4eba\u7684\u8840\u5e79\u7d30\u80de\uff0c\u6bcb\u9808\u5c0b\u627e\u6350\u9ad3\u8005\u3002\u79fb\u690d\u524d\uff0c\u91ab\u751f\u9810\u5148\u5b89\u6392\u5f9e\u75c5\u8005\u5468\u908a\u8840\u6db2\u63d0\u53d6\u8db3\u5920\u7684\u5468\u908a\u8840\u5e79\u7d30\u80de\uff08peripheral blood stem cells\uff09\uff0c\u7136\u5f8c\u8d85\u4f4e\u6eab\u51b7\u51cd\u81f3\u96f6\u4e0b150\u2103\u5b58\u653e\u5099\u7528\u3002\u82e5\u8981\u6536\u96c6\u8db3\u5920\u5468\u908a\u8840\u5e79\u7d30\u80de\uff0c\u5fc5\u9808\u5148\u63d0\u5347\u8840\u6db2\u5167\u5468\u908a\u8840\u5e79\u7d30\u80de\u6578\u91cf\uff0c\u7136\u5f8c\u5229\u7528\u7d30\u80de\u5206\u96e2\u6a5f\u6536\u96c6\u3002<\/p>\n

\u9aa8\u9ad3\u542b\u5927\u91cf\u9020\u8840\u5e79\u7d30\u80de\uff08haematopoietic stem cells\uff09\uff0c\u53ef\u8f49\u5316\u6210\u7d05\u8840\u7403\u3001\u767d\u8840\u7403\u53ca\u8840\u5c0f\u677f\uff0c\u4f46\u5468\u908a\u8840\u6db2\u5e73\u5e38\u53ea\u542b\u5fae\u91cf\u9020\u8840\u5e79\u7d30\u80de\u3002\u6b32\u63d0\u5347\u5468\u908a\u8840\u7684\u9020\u8840\u5e79\u7d30\u80de\u542b\u91cf\uff0c\u53ef\u6ce8\u5c04\u5347\u767d\u91dd\uff08G-CSF\uff09\uff1b\u5728\u6253\u5347\u767d\u91dd\u524d\uff0c\u5148\u6ce8\u5c04\u5316\u7642\u85e5\u7269\u74b0\u78f7\u9170\u80fa\uff08cyclophosphamide\uff09\uff0c\u6548\u679c\u66f4\u4f73\u3002\u82e5\u9020\u8840\u5e79\u7d30\u80de\u6578\u91cf\u4ecd\u7136\u4e0d\u8db3\uff0c\u5247\u53ef\u5728\u6536\u96c6\u5e79\u7d30\u80de\u524d\u4e00\u665a\u6ce8\u5c04\u57f9\u4f86\u6c99\u798f\uff08plerixafor\uff09\uff0c\u6709\u52a9\u9aa8\u9ad3\u91cb\u653e\u66f4\u591a\u9020\u8840\u5e79\u7d30\u80de\u5165\u5468\u908a\u8840\u6db2\u3002\u9aa8\u9ad3\u5e79\u7d30\u80de\u8868\u9762\u6709CXCR4\u53d7\u9ad4\uff0c\u9aa8\u9ad3\u57fa\u8cea\u7d30\u80de\uff08stromal cells\uff09\u5247\u6709\u57fa\u8cea\u7d30\u80de\u884d\u751f\u56e0\u5b50-1-\u03b1\u86cb\u767d\uff0c\u5169\u8005\u7d50\u5408\uff0c\u9632\u6b62\u5e79\u7d30\u80de\u96e2\u958b\u9aa8\u9ad3\uff1b\u57f9\u4f86\u6c99\u798f\u963b\u6b62\u7d50\u5408\uff0c\u4ee4\u9020\u8840\u5e79\u7d30\u80de\u5927\u91cf\u5165\u8840\uff0c\u6709\u52a9\u6210\u529f\u6536\u96c6\u8db3\u5920\u6578\u91cf\u7684\u9020\u8840\u5e79\u7d30\u80de\u4f9b\u79fb\u690d\u7528\u3002<\/p>\n

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\u79fb\u690d\u524d\u9700\u505a\u8d85\u5927\u5291\u91cf\u5316\u7642<\/strong><\/h2>\n

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