{"id":27778,"date":"2020-08-10T12:02:46","date_gmt":"2020-08-10T04:02:46","guid":{"rendered":"\/\/www.afterroberto.com\/?p=27778"},"modified":"2023-10-05T14:09:27","modified_gmt":"2023-10-05T06:09:27","slug":"%e3%80%90%e5%ad%90%e5%ae%ae%e9%ab%94%e7%99%8c%e3%80%91%e7%bd%95%e8%a6%8b%e5%a9%a6%e7%a7%91%e7%99%8c-%e5%be%b5%e7%8b%80%e7%9b%b8%e4%bc%bc-%e7%99%82%e6%b3%95%e5%a4%a7%e4%b8%8d%e5%90%8c","status":"publish","type":"post","link":"\/\/www.afterroberto.com\/%e3%80%90%e5%ad%90%e5%ae%ae%e9%ab%94%e7%99%8c%e3%80%91%e7%bd%95%e8%a6%8b%e5%a9%a6%e7%a7%91%e7%99%8c-%e5%be%b5%e7%8b%80%e7%9b%b8%e4%bc%bc-%e7%99%82%e6%b3%95%e5%a4%a7%e4%b8%8d%e5%90%8c\/","title":{"rendered":"\u3010\u5b50\u5bae\u9ad4\u764c\u3011\u7f55\u898b\u5a66\u79d1\u764c \u5fb5\u72c0\u76f8\u4f3c \u7642\u6cd5\u5927\u4e0d\u540c"},"content":{"rendered":"

\u3010\u660e\u5831\u5c08\u8a0a\u3011\u5973\u6027\u5e38\u898b\u764c\u75c7<\/a>\u4e2d\uff0c\u5b50\u5bae\u9ad4\u764c\u6392\u540d\u7b2c4\u3001\u5375\u5de2\u764c<\/a>\u6392\u540d\u7b2c6\u3001\u5b50\u5bae\u9838\u764c<\/a>\u6392\u540d\u7b2c9\uff1b\u800c\u9019\u4e9b\u5e38\u898b\u5a66\u79d1\u764c\u4e2d\uff0c\u6709\u4e9b\u500b\u6848\u8f03\u70ba\u7f55\u898b\uff0c\u816b\u7624\u540c\u6a23\u751f\u65bc\u5375\u5de2\u6216\u5b50\u5bae\uff0c\u5fb5\u72c0\u4e5f\u76f8\u4f3c\uff0c\u4f46\u6cbb\u7642\u65b9\u6848\u537b\u5927\u4e0d\u540c\u3002<\/p>\n

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\uff08\u660e\u5831\u88fd\u5716\uff09<\/figcaption><\/figure>\n

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\u500b\u68481\uff1a\u9673\u5973\u58eb\uff0c45\u6b72\uff0c\u7d0410\u5e74\u524d\u78ba\u8a3a\u60a3\u4e0a\u7f55\u898b\u7684\u5375\u5de2\u816b\u7624\u2014\u2014\u9846\u7c92\u7d30\u80de\u7624\uff08granulosa cell tumour\uff0cGCT\uff09\u3002\u56e0\u70ba\u662f\u7b2c1\u671f\uff0c\u4ea6\u8003\u616e\u5230\u751f\u80b2\u8a08\u5283\uff0c\u6240\u4ee5\u505a\u4e86\u55ae\u908a\u5375\u5de2\u53ca\u8f38\u5375\u7ba1\u5207\u9664\u624b\u8853\u3002\u4e4b\u5f8c\u4e00\u76f4\u5728\u5a66\u79d1\u91ab\u751f\u8655\u8986\u8a3a\uff0c\u4e26\u6c92\u6709\u5fa9\u767c\u8ff9\u8c61\u3002\u6700\u8fd1\u56e0\u70ba\u7d93\u671f\u6709\u9ede\u4e82\uff0c\u63a5\u53d7\u5f71\u50cf\u6aa2\u67e5\u6642\uff0c\u767c\u73fe\u53e6\u4e00\u908a\u5375\u5de2\u6709\u4e00\u500b4\u5398\u7c73\u816b\u7624\uff0c\u8179\u8154\u5169\u500b\u4f4d\u7f6e\u6709\u61f7\u7591\u8f49\u79fb\u7684\u8ff9\u8c61\u3002\u5979\u88ab\u8f49\u4ecb\u81f3\u5a66\u79d1\u816b\u7624\u79d1\u91ab\u751f\uff0c\u56e0\u70ba\u816b\u7624\u5c1a\u53ef\u4ee5\u5207\u9664\uff0c\u8a08\u5283\u5b50\u5bae\u5168\u5207\u9664\u52a0\u5269\u9918\u4e00\u908a\u5375\u5de2\u8f38\u5375\u7ba1\u5207\u9664\u624b\u8853\uff0c\u517c\u8179\u819c\u816b\u7624\u5207\u9664\u3002\u624b\u8853\u5f8c\u9700\u8981\u5316\u7642<\/a>\u3002<\/p>\n

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\u809a\u75db\u8981\u5c0f\u5fc3\u2014\u2014\u7121\u8ad6\u5c6c\u7f55\u898b\u3001\u5e38\u898b\u5375\u5de2\u764c\uff0c\u75c5\u5fb5\u7121\u7570\uff0c\u4e00\u822c\u6709\u809a\u8139\u3001\u809a\u75db\u3001\u7d93\u671f\u7570\u5e38\u3001\u5927\u5c0f\u4fbf\u4e0d\u9069\u7b49\u3002\uff08\u8a2d\u8a08\u5716\u7247\uff0c\u6a21\u7279\u5152\u8207\u6587\u4e2d\u63d0\u53ca\u75be\u75c5\u7121\u95dc\uff0cNattakorn Maneerat@iStockphoto\uff09<\/figcaption><\/figure>\n

 <\/p>\n

\u751f\u6b96\u7d30\u80de\u7624 \u75c5\u8005\u8f03\u5e74\u8f15<\/h2>\n

\u5375\u5de2\u764c\u5206\u591a\u985e\uff0c\u6700\u5e38\u898b\u662f\u4e0a\u76ae\u764c\uff08epithelial cancer\uff09\uff0c\u751f\u9577\u5728\u5375\u5de2\u7684\u5916\u6bbc\uff0c\u4f54\u6574\u9ad4\u5375\u5de2\u816b\u762490%\u3002\u53e6\u5916\uff0c\u670910%\u5c6c\u65bc\u975e\u4e0a\u76ae\u764c\u985e\u5225\uff08non-epithelial cancer\uff09\uff0c\u5305\u62ec\uff1a<\/p>\n

\u2027\u751f\u6b96\u7d30\u80de\u7624\uff08germ cell tumour\uff09\uff0c\u4e00\u822c\u767c\u751f\u572830\u6b72\u524d\uff0c\u5e73\u5747\u767c\u751f\u5e74\u9f6116\u81f320\u6b72\u3002<\/p>\n

\u2027\u6027\u817a\u9593\u8cea\u816b\u7624\uff08sex cord stromal tumour\uff09\uff0c\u96d6\u7136\u53ef\u898b\u65bc\u5e74\u8f15\u75c5\u4eba\uff0c\u4f46\u8f03\u591a\u662f\u5728\u63a5\u8fd1\u505c\u7d93\u6642\u767c\u751f\uff0c\u5e73\u5747\u5e74\u9f61\u7d0450\u6b72\u3002\u6027\u817a\u9593\u8cea\u816b\u7624\u4f86\u81ea\u5206\u88c2\u7d30\u80de\u7fa4\uff0c\u901a\u5e38\u5728\u5375\u5de2\u6bcd\u7d30\u80de\uff08oocytes\uff09\u5468\u570d\u7684\u7d44\u7e54\u7522\u751f\u3002\u9019\u985e\u816b\u7624\u6703\u7522\u751f\u985e\u56fa\u9187\u6fc0\u7d20\uff0c\u75c5\u4eba\u6709\u53ef\u80fd\u6703\u51fa\u73fe\u8377\u723e\u8499\u5206\u6ccc\u904e\u91cf\u7684\u75c5\u5fb5\u3002\u5b83\u4f54\u6574\u9ad4\u5375\u5de2\u764c3%\u81f35%\uff0c\u800c\u7576\u4e2d\u670960%\u662f\u7b2c\u4e00\u671f\u78ba\u8a3a\uff1b\u5176\u4e2d\u4e00\u985e\u578b\u5c31\u662f\u9846\u7c92\u7d30\u80de\u7624\u3002<\/p>\n

\u7121\u8ad6\u5c6c\u7f55\u898b\u3001\u5e38\u898b\u5375\u5de2\u764c\uff0c\u75c5\u5fb5\u90fd\u7121\u7570\uff0c\u4e00\u822c\u6709\u809a\u8139\u3001\u809a\u75db\u3001\u7d93\u671f\u7570\u5e38\uff0c\u6216\u56e0\u76c6\u8154\u816b\u7624\u5f15\u8d77\u58d3\u529b\u800c\u51fa\u73fe\u75c5\u5fb5\u5982\u5927\u5c0f\u4fbf\u4e0d\u9069\u3002\u60a3\u8005\u5fc5\u9808\u505a\u5f71\u50cf\u6aa2\u67e5\uff0c\u5305\u62ec\u76c6\u8154\u8d85\u8072\u6ce2\u3001\u96fb\u8166\u6383\u63cf\uff0c\u82e5\u61f7\u7591\u662f\u665a\u671f\u764c\u75c7\u53ef\u4ee5\u518d\u52a0\u6b63\u96fb\u5b50\u6383\u63cf\u3002\u764c\u6307\u6578\u5728\u7f55\u898b\u985e\u5225\u4e2d\uff0c\u6709\u91dd\u5c0d\u751f\u6b96\u7d30\u80de\u764c\u7684AFP\u3001HCG\u3001LDH\uff0c\u4ee5\u53ca\u91dd\u5c0d\u9846\u7c92\u7d30\u80de\u7624\u7684inhibin\u3002\u764c\u75c7\u5206\u671f\u5247\u548c\u4e0a\u76ae\u5375\u5de2\u764c\u4e00\u6a23\uff0c\u7b2c1\u671f\u5c40\u9650\u5728\u5375\u5de2\uff1b\u7b2c2\u671f\u5f71\u97ff\u76c6\u8154\u5176\u4ed6\u7d44\u7e54\uff0c\u4f8b\u5982\u5b50\u5bae\u6216\u8f38\u5375\u7ba1\uff1b\u7b2c3\u671f\u5f71\u97ff\u6dcb\u5df4\u3001\u76c6\u8154\u4ee5\u5916\u7684\u8179\u819c\u7d44\u7e54\uff1b\u7b2c4\u671f\u6709\u80ba\u7a4d\u6c34\u6216\u9060\u7aef\u5668\u5b98\u8f49\u79fb\u3002<\/p>\n

 <\/p>\n

70%\u81f390%\u5c6c\u7b2c1\u671f<\/h2>\n

\u6cbb\u7642\u65b9\u9762\uff0c\u670970%\u81f390%\u7f55\u898b\u5375\u5de2\u764c\u5c6c\u65bc\u7b2c1\u671f\u3002\u5c24\u5176\u662f\u751f\u6b96\u7d30\u80de\u7624\uff0c\u75c5\u4eba\u591a\u70ba\u5e74\u7d00\u8f03\u8f15\uff0c\u81ea\u7136\u5e0c\u671b\u4fdd\u5b58\u751f\u6b96\u80fd\u529b\uff0c\u6240\u4ee5\u6703\u505a\u5207\u9664\u55ae\u908a\u5375\u5de2\u53ca\u8f38\u5375\u7ba1\u624b\u8853\u3002\u4f46\u5c0d\u665a\u671f\u6216\u505c\u7d93\u5f8c\u5973\u58eb\uff0c\u4e00\u500b\u5fb9\u5e95\u7684\u5b50\u5bae\u53ca\u5169\u908a\u5375\u5de2\u8f38\u5375\u7ba1\u5207\u9664\u624b\u8853\uff0c\u662f\u6a19\u6e96\u7684\u6cbb\u7642\u65b9\u6848\u3002<\/p>\n

\u5982\u679c\u6027\u817a\u9593\u8cea\u816b\u7624\u5c6c\u7b2c2\u671f\u4ee5\u4e0a\uff0c\u6216\u7b2c1\u671f\u5df2\u5b58\u5728\u98a8\u96aa\u56e0\u7d20\uff0c\u4f8b\u5982\u7b2c1C\u671f\uff0c\u7d30\u80de\u5206\u5316\u5dee\uff08poorly differentiated\uff09\uff0c\u4ee3\u8868\u9ad8\u5ea6\u60e1\u6027\u3001\u64f4\u6563\u98a8\u96aa\u8f03\u9ad8\uff0c\u5c31\u5fc5\u9808\u63a5\u53d7\u7d9c\u5408\u9251\u985e\u5316\u7642\u65b9\u6848\u3002\u81f3\u65bc\u5fa9\u767c\u75c5\u4eba\u53ef\u63a1\u7528\u4e8c\u7dda\u5316\u7642\uff0c\u4f8b\u5982\u7d2b\u6749\u9187\u7d9c\u5408\u9251\u985e\u7684\u6cbb\u7642\u3002<\/p>\n

\u800c\u751f\u6b96\u7d30\u80de\u7624\u7684\u75c5\u4eba\uff0c\u9664\u4e861A\u671f\u672a\u6210\u719f\u578b\u7578\u80ce\u7624\uff08immature teratoma\uff09\u548c\u751f\u6b96\u7d30\u80de\u4e0d\u826f\u7624\uff08dysgerminoma\uff09\uff0c\u5176\u9918\u90fd\u5fc5\u9808\u63a5\u53d7\u624b\u8853\u5f8c\u7684\u7d9c\u5408\u5316\u7642\u3002\u6709\u6548\u6cbb\u7642\u662fBEP\u65b9\u6848\uff08bleomycin\u3001etoposide\u548ccarboplatin\uff09\uff0c3\u81f34\u500b\u7642\u7a0b\u3002\u5118\u7ba1\u662f\u5fa9\u767c\u7684\u751f\u6b96\u7d30\u80de\u7624\uff0c\u4ecd\u6709\u6a5f\u6703\u5c0d\u5316\u7642\u654f\u611f\uff08chemotherapy sensitive\uff09\u800c\u9054\u5230\u6839\u6cbb\u7684\u6548\u679c\u3002<\/p>\n

 <\/p>\n

\u7f55\u898b\u5b50\u5bae\u9ad4\u764c \u816b\u7624\u4e00\u822c\u8f03\u60e1<\/h2>\n

\u500b\u68482\uff1a\u5433\u5973\u58eb\uff0c40\u6b72\uff0c\u4e00\u5929\u7a81\u7136\u6478\u5230\u809a\u5b50\u6709\u4e00\u500b\u9686\u584a\uff0c\u8d85\u8072\u6ce2\u6aa2\u67e5\u767c\u73fe\u4e00\u500b10\u5398\u7c73\u5b50\u5bae\u816b\u7624\u3002\u96a8\u5373\u8f49\u4ecb\u505a\u78c1\u529b\u5171\u632f\u548c\u6b63\u96fb\u5b50\u6383\u63cf\u6aa2\u67e5\uff0c\u767c\u73fe\u816b\u7624\u5f88\u5927\u53ef\u80fd\u6e90\u81ea\u5b50\u5bae\u808c\u8089\u5c64\u7684\u60e1\u6027\u816b\u7624\u3002\u5979\u63a5\u53d7\u4e86\u5b50\u5bae\u53ca\u5169\u908a\u5375\u5de2\u8f38\u5375\u7ba1\u5207\u9664\u624b\u8853\uff0c\u518d\u52a0\u4e0a\u6dcb\u5df4\u5207\u9664\u624b\u8853\u3002<\/p>\n

\u5b50\u5bae\u9ad4\u764c\u4e2d\uff0c\u8d85\u904e\u4e5d\u6210\u662f\u5b50\u5bae\u5167\u819c\u764c\uff0c\u9918\u4e0b\u5c6c\u5b50\u5bae\u60e1\u6027\u8089\u7624\u3002\u5433\u5973\u58eb\u7684\u75c5\u7406\u5831\u544a\u986f\u793a\uff0c\u816b\u7624\u5c6c\u65bc\u5f8c\u8005\u7684\u5b50\u5bae\u5e73\u6ed1\u808c\u60e1\u6027\u816b\u7624\uff08uterine leiomyosarcoma\uff09\u3002\u53ef\u60dc\u7684\u662f\uff0c\u8853\u5f8c3\u661f\u671f\u7684\u5f71\u50cf\u986f\u793a\uff0c\u816b\u7624\u5df2\u7d93\u591a\u767c\u6027\u8f49\u79fb\u5230\u80ba\u90e8\u3002\u5433\u5973\u58eb\u96a8\u5373\u958b\u59cb\u7d9c\u5408\u5316\u7642\uff0c\u5305\u62ec\u7d05\u9709\u7d206\u500b\u7642\u7a0b\u4e4b\u5f8c\uff0c\u816b\u7624\u60c5\u51b5\u6539\u5584\u3002\u5b8c\u6210\u5316\u7642\u5f8c\uff0c\u5979\u5229\u75283\u661f\u671f\u5047\u671f\u548c\u7236\u6bcd\u65c5\u904a\u3002\u56de\u6e2f\u5f8c\u4e00\u76f4\u76e3\u5bdf\u75c5\u60c5\uff0c1\u500b\u6708\u5f8c\u767c\u73fe\u816b\u7624\u518d\u8f49\u79fb\u5230\u8179\u819c\uff0c\u63a5\u53d7\u4e86\u4e8c\u7dda\u5316\u7642\uff1b\u540c\u6642\u63a5\u53d7\u57fa\u56e0\u6e2c\u5e8f\u5f8c\uff0c\u63a1\u7528\u4e86\u6a19\u9776\u6cbb\u7642\u3002<\/p>\n

 <\/p>\n

\u57fa\u56e0\u7a81\u8b8a \u5fa9\u767c\u98a8\u96aa\u8f03\u9ad8<\/h2>\n

\u5728\u5b50\u5bae\u5167\u819c\u764c\u4e2d\uff0c30%\u5c6c\u65bc\u8f03\u7f55\u898b\u7684\u975e\u5b50\u5bae\u5167\u819c\u6a23\uff08non-endometrioid\uff09\u764c\u75c7\uff1b\u9019\u5305\u62ec\u6f3f\u6db2\u6027\u764c\uff08serous\uff09\u3001\u4eae\u7d30\u80de\u764c\uff08clear cell\uff09\u8207\u8089\u7624\u764c\uff08carcinosarcoma\uff09\u3002\u5b83\u5011\u4e00\u822c\u60e1\u6027\u7a0b\u5ea6\u9ad8\uff08high grade\uff09\uff0c\u78ba\u8a3a\u6642\u901a\u5e38\u5df2\u5728\u5f8c\u671f\uff08\u7b2c3\u30014\u671f\uff09\uff0c\u6709\u6dcb\u5df4\u8f49\u79fb\u7684\u98a8\u96aa\u8f03\u9ad8\uff0c\u7d30\u80de\u7279\u6027\u5c6c\u65bc\u96cc\u6fc0\u7d20\u53d7\u9ad4\uff08estrogen receptor\uff09\u9670\u6027\u7684\u985e\u5225\u3002\u53e6\u5916\uff0c\u76f8\u6bd4\u65bc\u8f03\u5e38\u898b\u7684\u5b50\u5bae\u5167\u819c\u6a23\u764c\uff0c\u9019\u4e9b\u7f55\u898b\u985e\u578b\u64c1\u6709\u4e0d\u540c\u57fa\u56e0\u7a81\u8b8a\uff0c\u4f8b\u5982\u6f3f\u6db2\u6027\u764c\u6709\u8f03\u9ad8\u7684\u4e0a\u76ae\u56e0\u5b50\u53d7\u9ad4\uff08HER2\uff09\u7a81\u8b8a\uff0c\u4ee3\u8868\u6709\u76f8\u61c9\u6a19\u9776\u6cbb\u7642\u53ef\u7528\u3002\u9019\u7a2e\u764c\u75c7\u7531\u65bc\u60e1\u6027\u7a0b\u5ea6\u9ad8\uff0c\u5fa9\u767c\u98a8\u96aa\u8f03\u9ad8\uff0c\u5373\u4f7f\u5c6c\u6700\u65e9\u7684\u7b2c1\u671f\uff0c\u4ecd\u7136\u6703\u4ee5\u5b50\u5bae\u548c\u5169\u908a\u5375\u5de2\u8f38\u5375\u7ba1\u5207\u9664\u8853\u4f5c\u70ba\u4e3b\u8981\u7684\u6839\u6cbb\u7b56\u7565\u3002\u53e6\u5916\u4ea6\u9700\u8981\u8996\u4e4e\u4e0d\u540c\u7684\u5fa9\u767c\u56e0\u7d20\uff0c\u800c\u8003\u616e\u7528\u5316\u7642\u3001\u96fb\u7642\uff08\u5305\u62ec\u76c6\u8154\u9ad4\u5916\u96fb\u7642\uff0c\u6216\u8fd1\u8ddd\u96e2\u653e\u5c04\u6cbb\u7642\uff09\u91ab\u6cbb\u3002<\/p>\n

 <\/p>\n

\u57fa\u56e0\u6e2c\u5e8f\u914d\u5408\u65b0\u6a19\u9776\u6cbb\u7642<\/h2>\n

\u5b50\u5bae\u60e1\u6027\u8089\u7624\u975e\u5e38\u7f55\u898b\uff0c\u4f54\u5c11\u65bc10%\uff0c\u5305\u62ec\u5e73\u6ed1\u808c\u60e1\u6027\u816b\u7624\uff08leiomyosarcoma\uff09\u3001\u5b50\u5bae\u5167\u819c\u57fa\u8cea\u60e1\u6027\u8089\u7624\uff08endometrial stromal sarcoma\uff09\u53ca\u9ad8\u5ea6\u60e1\u6027\u672a\u5206\u5316\u8089\u7624 \uff08high grade undifferentiated sarcoma\uff09\u3002\u9664\u4e86\u6839\u6cbb\u6027\u624b\u8853\u5916\uff0c\u5728\u8853\u5f8c\u6216\u5fa9\u767c\u5f8c\uff0c\u8996\u4e4e\u5371\u96aa\u56e0\u7d20\u548c\u5206\u5316\u7a0b\u5ea6\uff0c\u6c7a\u5b9a\u5316\u7642\u3001\u653e\u5c04\u6cbb\u7642\u6216\u8377\u723e\u8499\u6cbb\u7642\u3002\u9019\u985e\u816b\u7624\uff0c\u5c24\u5176\u5728\u9ad8\u60e1\u6027\u7a0b\u5ea6\uff08high grade\uff09\u985e\u5225\u4e2d\uff0c\u5fa9\u767c\u98a8\u96aa\u5f88\u9ad8\uff0c\u9664\u4e86\u50b3\u7d71\u5316\u7642\u4e4b\u5916\uff0c\u4e5f\u6703\u904b\u7528\u591a\u9776\u9ede\u7684\u916a\u80fa\u9178\u6fc0\u9176\u6291\u5236\u5291\uff08multi kinase inhibitor\uff09\uff0c\u548c\u900f\u904e\u57fa\u56e0\u6e2c\u5e8f\u914d\u5408\u65b0\u7684\u6a19\u9776\u6cbb\u7642\uff0c\u5e0c\u671b\u70ba\u75c5\u4eba\u5e36\u4f86\u63a7\u5236\u75c5\u60c5\u7684\u65b0\u6a5f\u6703\u3002<\/p>\n

 <\/p>\n

\u6587\uff1a\u5f35\u5929\u6021\uff08\u9999\u6e2f\u5927\u5b78\u81e8\u7240\u816b\u7624\u5b78\u7cfb\u540d\u8b7d\u81e8\u7240\u52a9\u7406\u6559\u6388\uff09
\n\u7de8\u8f2f\uff1a\u8521\u66c9\u5f64
\n\u96fb\u90f5\uff1afeature@mingpao.com<\/p>\n