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\u914d\u5408\u5316\u7642 \u76f8\u8f14\u76f8\u6210<\/h2>\n

\u82e5\u60a3\u4e0a\u9c57\u72c0\u7d30\u80de\u764c\u6216\u817a\u6027\u80ba\u764c\uff0c\u800c\u764c\u7d30\u80de\u6a23\u672cPDL1\u6aa2\u6e2c\u6c34\u5e73\u5f88\u9ad8\uff08\u4e0d\u4f4e\u65bc50%\uff09\uff0c\u6cbb\u7642\u4e0a\u53ef\u76f4\u63a5\u4f7f\u7528\u514d\u75ab\u7642\u6cd5\uff08PD1\/PDL1 checkpoint inhibitors\uff09\uff0c\u5982\u5339\u535a\u5229\u7d44\u55ae\u6297\uff08pembrolizumab\uff09\uff0c\u4e00\u822c\u6cbb\u7642\u53cd\u61c9\u975e\u5e38\u660e\u986f\uff0c\u53ef\u4ee5\u514d\u537b\u5316\u7642\u3002\u82e5PDL1\u6aa2\u6e2c\u6c34\u5e73\u4f4e\uff0c\u55ae\u4f7f\u7528\u514d\u75ab\u7642\u6cd5\u7684\u7642\u6548\u4e26\u4e0d\u986f\u8457\uff1b\u4f46\u82e5\u540c\u6642\u914d\u5408\u5316\u7642\uff0c\u6709\u76f8\u8f14\u76f8\u6210\u7684\u6548\u679c\u3002\u8209\u4f8b\u8aaa\uff0c\u5c0d\u4ed8\u5c0f\u7d30\u80de\u80ba\u764c\uff0c\u4f7f\u7528\u5316\u7642\u7d44\u5408\u9806\u9251+\u4f9d\u6258\u6cca\u82f7\uff08cisplatin-etoposide\uff09\uff0c\u518d\u52a0\u4e0a\u514d\u75ab\u6cbb\u7642\u85e5\u7269\u963f\u7279\u73e0\u55ae\u6297\uff08atezolizumab\uff09\uff0c\u8b49\u5be6\u6bd4\u55ae\u7528\u5316\u7642\u7684\u7642\u6548\u66f4\u4f73\u3002\u53c8\u4f8b\u5982\u817a\u6027\u80ba\u764c\uff0c\u53ef\u4f7f\u7528\u5316\u7642\u7d44\u5408\u57f9\u7f8e\u66f2\u585e+\u5361\u9251\uff08pemetrexed-carboplatin\uff09\uff0c\u518d\u52a0\u4e0a\u5339\u535a\u5229\u7d44\u55ae\u6297\uff0c\u7642\u6548\u6bd4\u55ae\u7528\u5316\u7642\u5927\u5927\u63d0\u5347\u3002<\/p>\n

\u6709\u90e8\u5206\u5728\u4e00\u4e8c\u7dda\u6cbb\u7642\u4f7f\u7528\u53e3\u670d\u6a19\u9776\u85e5\u7684\u75c5\u4eba\uff0c\u7576\u85e5\u5931\u6548\u5f8c\uff0c\u540c\u6642\u4f7f\u7528\u5316\u7642\u548c\u514d\u75ab\u7642\u6cd5\uff0c\u7642\u6548\u4ea6\u76f8\u7576\u986f\u8457\uff0c\u66f4\u52dd\u904e\u5f80\u55ae\u7d14\u4f7f\u7528\u5316\u7642\u3002\u9999\u6e2f\u5927\u5b78\u505a\u4e86\u4e00\u500b\u4e8c\u671f\u81e8\u7240\u6e2c\u8a66\uff0c\u7d50\u679c\u5c07\u5728\u570b\u969b\u6703\u8b70\u4e2d\u767c\u8868\u3002\u7121\u8ad6\u662f\u54ea\u4e00\u7a2e\u80ba\u764c\uff0c\u514d\u75ab\u7642\u6cd5\u90fd\u6703\u6162\u6162\u6210\u70ba\u6cbb\u7642\u9aa8\u5e79\u3002<\/p>\n

\u5316\u7642\uff1a\u8207\u514d\u75ab\u6cbb\u7642\u96d9\u7ba1\u9f4a\u4e0b<\/h2>\n

\u63d0\u8d77\u5316\u7642\uff0c\u5f88\u591a\u75c5\u4eba\u90fd\u805e\u98a8\u8272\u8b8a\uff0c\u4e3b\u8981\u56e0\u70ba\u526f\u4f5c\u7528\u4e0d\u5c11\u3002\u5176\u5be6\u73fe\u5728\u5316\u7642\u85e5\u7269\u5df2\u7d93\u5927\u70ba\u6539\u9032\uff0c\u9069\u7576\u4f7f\u7528\u5316\u7642\uff0c\u7279\u5225\u662f\u914d\u5408\u514d\u75ab\u7642\u6cd5\u4f7f\u7528\uff0c\u5c0d\u65bc\u6cbb\u7642\u80ba\u764c\u662f\u5229\u591a\u65bc\u5f0a\u3002\u4e00\u822c\u5e38\u7528\u5316\u7642\u85e5\u7269\u6709\u9806\u9251\u3001\u5361\u9251\u3001\u7d2b\u6749\u9187\uff08paclitaxel\uff09\u3001\u57f9\u7f8e\u66f2\u585e\u3001\u5409\u897f\u4ed6\u6ff1\uff08gemcitabine\uff09\u3001\u4f9d\u6258\u6cca\u82f7\u7b49\u3002\u91ab\u751f\u9078\u7528\u5316\u7642\u85e5\u6642\uff0c\u9664\u4e86\u8003\u616e\u80ba\u764c\u7a2e\u985e\uff0c\u4ea6\u8981\u8003\u616e\u75c5\u4eba\u8eab\u9ad4\u72c0\u51b5\u3001\u809d\u814e\u529f\u80fd\u7b49\uff0c\u5f9e\u800c\u9078\u64c7\u6700\u5408\u9069\u7684\u5316\u7642\u85e5\u3002\u5316\u7642\u4e00\u822c\u9700\u89816\u500b\u5468\u671f\uff0c\u6bcf\u500b\u5468\u671f\u7d043\u661f\u671f\uff0c\u6240\u4ee5\u75c5\u4eba\u6703\u63a5\u53d74\u500b\u6708\u5de6\u53f3\u7684\u5316\u7642\u3002\u4e4b\u5f8c\u6703\u56e0\u61c9\u60c5\u51b5\u505c\u85e5\uff0c\u9032\u5165\u85e5\u7269\u5047\u671f\uff08drug holiday\uff09\u3002\u53e6\u5916\uff0c\u67d0\u4e9b\u85e5\u7269\u5982\u57f9\u7f8e\u66f2\u585e+\u5361\u9251\u6df7\u5408\u5316\u7642\uff0c\u57284\u81f36\u500b\u5468\u671f\u4e4b\u5f8c\uff0c\u53ef\u4ee5\u9078\u64c7\u55ae\u4e00\u85e5\u7269\u57f9\u7f8e\u66f2\u585e\u7528\u4f5c\u9577\u671f\u7dad\u6301\u6027\u5316\u7642\uff08maintenance chemotherapy\uff09\uff0c\u6709\u52a9\u963b\u6b62\u75c5\u60c5\u60e1\u5316\u3002<\/p>\n

\u9aa8\u91dd\uff1a\u6e1b\u4f4e\u764c\u7d30\u80de\u8f49\u79fb\u9aa8\u9abc<\/h2>\n

\u9664\u4e86\u4e0a\u8ff0\u91dd\u5c0d\u816b\u7624\u7684\u6cbb\u7642\u5916\uff0c\u4ea6\u6709\u4fdd\u8b77\u9aa8\u9abc\uff0c\u6e1b\u4f4e\u764c\u7d30\u80de\u8f49\u79fb\u5230\u9aa8\u9abc\u7684\u300c\u9aa8\u91dd\u300d\uff1a\u96d9\u78f7\u9178\u9e7d\uff08bisphosphonate\uff09\u548c\u5730\u8afe\u55ae\u6297\uff08denosumab\uff09\u3002\u6b64\u5916\uff0c\u9069\u7576\u5229\u7528\u96fb\u7642\uff0c\u7279\u5225\u662f\u9ad8\u7cbe\u5ea6\u7acb\u9ad4\u5b9a\u4f4d\u653e\u5c04\u7dda\u6cbb\u7642\uff08stereotactic body radiation therapy\uff0cSBRT\uff09\uff0c\u5c0d\u67d0\u4e9b\u300c\u5be1\u8f49\u79fb\u300d\u7684\u75c5\u4eba\u751a\u81f3\u53ef\u4ee5\u9054\u5230\u75ca\u7652\u7684\u6548\u679c\uff08\u5728\u4e4b\u524d\u7684\u5c08\u6b04\u6587\u7ae0\u4e2d\u6709\u8a73\u7d30\u8b1b\u8ff0\uff09\u3002<\/p>\n

\u75c5\u4eba\u807d\u904e\u89e3\u91cb\u4e4b\u5f8c\uff0c\u5fc3\u60c5\u7a0d\u70ba\u653e\u9b06\u3002\u9996\u5148\u5b89\u6392\u5728\u4ed6\u65e9\u524d\u62bd\u53d6\u7684\u816b\u7624\u7d30\u80de\u6a23\u672c\uff0c\u4f5c\u57fa\u56e0\u6e2c\u8a66\u548cPDL1\u6c34\u5e73\u6aa2\u6e2c\uff0c\u6536\u5230\u5831\u544a\u5f8c\uff0c\u624d\u63a2\u8a0e\u4e0b\u4e00\u6b65\u7684\u6cbb\u7642\u65b9\u6848\u3002<\/p>\n

\u6587\uff1a\u8607\u5b50\u8b19\uff08\u9999\u6e2f\u5927\u5b78\u81e8\u7240\u816b\u7624\u5b78\u7cfb\u81e8\u7240\u52a9\u7406\u6559\u6388\uff09<\/p>\n

\u7de8\u8f2f\uff1a\u6797\u66c9\u6167<\/p>\n

\u96fb\u90f5\uff1afeature@mingpao.com<\/a><\/p>\n

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\u5c08\u984c\u7cfb\u5217\u6587\u7ae0<\/h3>\n<\/section>\n