{"id":23202,"date":"2020-01-06T12:27:09","date_gmt":"2020-01-06T04:27:09","guid":{"rendered":"\/\/www.afterroberto.com\/?p=23202"},"modified":"2020-01-15T15:01:34","modified_gmt":"2020-01-15T07:01:34","slug":"%e6%a3%98%e6%89%8b%e4%b8%89%e9%99%b0%e6%80%a7%e4%b9%b3%e7%99%8c-%e6%96%b0%e6%ad%a6%e5%99%a8%e5%bb%b6%e5%91%bd","status":"publish","type":"post","link":"\/\/www.afterroberto.com\/%e6%a3%98%e6%89%8b%e4%b8%89%e9%99%b0%e6%80%a7%e4%b9%b3%e7%99%8c-%e6%96%b0%e6%ad%a6%e5%99%a8%e5%bb%b6%e5%91%bd\/","title":{"rendered":"\u68d8\u624b\u4e09\u9670\u6027\u4e73\u764c \u65b0\u6b66\u5668\u5ef6\u547d"},"content":{"rendered":"<figure id=\"attachment_23229\" aria-describedby=\"caption-attachment-23229\" style=\"width: 707px\" class=\"wp-caption aligncenter\"><a href=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2020\/01\/a6dc9bd5a2e4430f134fc0fecf5637ba.jpg\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-23229 size-full\" src=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2020\/01\/a6dc9bd5a2e4430f134fc0fecf5637ba.jpg\" alt=\"\" width=\"707\" height=\"718\" title=\"\" srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2020\/01\/a6dc9bd5a2e4430f134fc0fecf5637ba.jpg 707w, \/\/www.afterroberto.com\/wp-content\/uploads\/2020\/01\/a6dc9bd5a2e4430f134fc0fecf5637ba-295x300.jpg 295w, \/\/www.afterroberto.com\/wp-content\/uploads\/2020\/01\/a6dc9bd5a2e4430f134fc0fecf5637ba-148x150.jpg 148w, \/\/www.afterroberto.com\/wp-content\/uploads\/2020\/01\/a6dc9bd5a2e4430f134fc0fecf5637ba-246x250.jpg 246w\" sizes=\"(max-width: 707px) 100vw, 707px\" \/><\/a><figcaption id=\"caption-attachment-23229\" class=\"wp-caption-text\">\u4e73\u764c\u5e74\u8f15\u5316\u2014\u2014\u6839\u64da\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc32017\u5e74\u6578\u64da\uff0c\u4e73\u764c\u60a3\u8005\u5e73\u5747\u5e74\u9f61\u70ba57\u6b72\uff0c\u4f46\u6108\u4f86\u6108\u591a\u5e74\u8f15\u5a66\u5973\u78ba\u8a3a\u60a3\u4e0a\u4e73\u764c\u3002\uff08rustycloud@iStockphoto\uff09<\/figcaption><\/figure>\n<p>\u3010\u660e\u5831\u5c08\u8a0a\u3011\u9078\u64c7\u764c\u75c7\u7642\u6cd5\uff0c\u9664\u4e86\u8003\u616e\u764c\u75c7\u5206\u671f\u548c\u816b\u7624\u5927\u5c0f\uff0c\u73fe\u4eca\u66f4\u6703\u8003\u616e\u764c\u7d30\u80de\u7a2e\u985e\uff0c\u4ee5\u6c7a\u5b9a\u662f\u7528\u5316\u7642\u3001\u6a19\u9776\u6cbb\u7642\u3001\u514d\u75ab\u6cbb\u7642\u3002<\/p>\n<p>\u4e09\u9670\u6027<a href=\"\/\/www.afterroberto.com\/?s=%E4%B9%B3%E7%99%8C\" rel=\"nofollow\">\u4e73\u764c<\/a>\u7531\u65bc\u6c92\u6709\u91dd\u5c0d\u6027\u7684\u85e5\u7269\u6cbb\u7642\uff0c\u4e14\u8f49\u79fb\u53ca\u5fa9\u767c\u98a8\u96aa\u8f03\u9ad8\uff0c\u4e00\u76f4\u88ab\u8996\u70ba\u8f03\u68d8\u624b\u7684\u4e73\u764c\u3002\u4e0d\u904e\u6700\u8fd1\u6709\u7814\u7a76\u767c\u73fe\uff0c\u65b0\u7684\u514d\u75ab\u6cbb\u7642\u548c\u6a19\u9776\u85e5\u7269\uff0c\u5206\u5225\u5ef6\u9577\u75c5\u4eba\u7684\u7121\u60e1\u5316\u5b58\u6d3b\u671f2.5\u81f32.8\u500b\u6708\u3002<\/p>\n<p>\u4e73\u764c\u662f\u9999\u6e2f\u5a66\u5973\u6700\u5e38\u60a3\u4e0a\u7684\u764c\u75c7\u3002\u6839\u64da2017\u5e74\u9999\u6e2f\u764c\u75c7\u7d71\u8a08\uff0c\u4e73\u817a\u764c\u4f54\u5168\u6e2f\u5a66\u5973\u764c\u75c727%\uff0c\u5165\u4fb5\u6027\u4e73\u817a\u764c\u7684\u65b0\u75c7\u500b\u6848\u8df3\u5347\u81f34373\u5b97\uff0c\u6bd42016\u5e74\u4e0a\u53476.5%\u3002\u8981\u6cbb\u7642\u4e73\u764c\uff0c\u53d6\u6c7a\u65bc\u8a31\u591a\u56e0\u7d20\uff0c\u4f8b\u5982\uff1a\u5e74\u9f61\u3001\u66f4\u5e74\u671f\u524d\u5f8c\u3001\u5065\u5eb7\u72c0\u51b5\u3001\u4e73\u764c\u5206\u671f\u3001\u816b\u7624\u5927\u5c0f\u3001\u6dcb\u5df4\u5f71\u97ff\u548c\u764c\u7d30\u80de\u5206\u985e\u7b49\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u591a40\u81f350\u6b72\u767c\u75c5 \u764c\u7d30\u80de\u5feb\u901f\u8f49\u79fb<\/h2>\n<p>\u9999\u6e2f\u6574\u9ad4\u4e73\u764c\u500b\u6848\u4e4b\u4e2d\uff0c\u7d0410%\u81f315%\u5c6c\u65bc\u4e09\u9670\u6027\u4e73\u764c\uff08Triple-negative breast cancer\uff0cTNBC\uff09\u3002\u300c\u4e09\u9670\u6027\u300d\u662f\u6307\u764c\u7d30\u80de\u5c0d\u96cc\u6fc0\u7d20\u53d7\u9ad4\uff08ER\uff09\u3001\u9ec3\u9ad4\u916e\u53d7\u9ad4\uff08PR\uff09\u3001\u4e0a\u76ae\u751f\u9577\u7d20\u56e0\u5b50\uff08HER2\uff09\u90fd\u5448\u9670\u6027\u3002\u82e5\u662f\u6709\u524d\u5169\u7a2e\u8377\u723e\u8499\u53d7\u9ad4\uff08\u96cc\u6fc0\u7d20\u3001\u9ec3\u9ad4\u916e\u53d7\u9ad4\uff09\u7684\u4e73\u764c\uff0c\u53ef\u4ee5\u63a1\u7528\u8377\u723e\u8499\u6cbb\u7642\uff1b\u6709HER2\u7684\u4e73\u764c\uff0c\u5247\u53ef\u4ee5\u7528\u6297HER2\u7684\u6a19\u9776\u6cbb\u7642\u3002\u4f46\u5c0d\u4ed8\u4e09\u9670\u6027\u4e73\u764c\uff0c\u8377\u723e\u8499\u6cbb\u7642\u53ca\u6a19\u9776\u6cbb\u7642\u7686\u7121\u6548\uff0c\u53ea\u80fd\u501a\u8cf4\u5316\u5b78\u6cbb\u7642\u4f5c\u70ba\u6297\u764c\u85e5\u7269\u3002<\/p>\n<p>\u4e09\u9670\u6027\u4e73\u764c\u591a\u572840\u81f350\u6b72\u767c\u75c5\uff0c\u6bd4\u4e00\u822c\u7684\u4e73\u764c\u60a3\u8005\u5e74\u8f15\u3002\u53e6\u5916\uff0c\u4e73\u623f\u816b\u7624\u6703\u8f03\u5927\uff0c\u764c\u7d30\u80de\u4ea6\u8f03\u5147\u60e1\uff0c\u5bb9\u6613\u8f49\u79fb\u6dcb\u5df4\u7d50\uff0c\u51fa\u73fe\u9060\u8655\u8f49\u79fb\u7684\u6642\u9593\u8f03\u77ed\uff0c\u6b7b\u4ea1\u7387\u8f03\u9ad8\uff1b\u5373\u4f7f\u7d93\u904e\u6cbb\u7642\uff0c\u99965\u5e74\u5167\u4ecd\u6709\u8f03\u9ad8\u7684\u5fa9\u767c\u98a8\u96aa\uff0c\u6240\u4ee5\u4e00\u76f4\u88ab\u8996\u70ba\u8f03\u68d8\u624b\u7684\u4e73\u764c\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u514d\u75ab\u6cbb\u7642\u00d7\u5316\u7642 \u986f\u8457\u6e1b\u60e1\u5316\u98a8\u96aa<\/h2>\n<p>\u96d6\u7136\u76ee\u524d\u5316\u5b78\u6cbb\u7642\u662f\u4e09\u9670\u6027\u4e73\u764c\u7684\u6a19\u6e96\u6cbb\u7642\uff0c\u4f46\u91ab\u5b78\u754c\u4e00\u76f4\u7a4d\u6975\u7814\u7a76\u65b0\u85e5\uff0c\u5e0c\u671b\u53ef\u589e\u5f37\u5c0d\u6b64\u60e1\u75be\u7684\u7642\u6548\u3002\u5176\u4e2d\uff0c\u5c0d\u4ed8\u9ed1\u8272\u7d20\u7d30\u80de\u764c\u3001\u80ba\u764c\u3001\u814e\u764c\u7b49\u6709\u986f\u8457\u6210\u6548\u7684\u514d\u75ab\u6cbb\u7642\uff0c\u5728\u6cbb\u7642\u4e09\u9670\u6027\u4e73\u764c\u4e2d\u4e5f\u6709\u65b0\u7a81\u7834\u3002<\/p>\n<p>\u4e00\u500b\u591a\u570b\u53c3\u8207\u7684\u7b2c\u4e09\u671f\u81e8\u7240\u7814\u7a76\uff0c\u5c07902\u540d\u7b2c\u56db\u671f\u8f49\u79fb\u6027\u6216\u4e0d\u53ef\u624b\u8853\u6cbb\u7642\u7684\u4e09\u9670\u6027\u4e73\u764c\u60a3\u8005\u5206\u70ba\u5169\u7d44\uff0c\u4e00\u7d44\u60a3\u8005\u53ea\u63a1\u7528\u7d0d\u7c73\u767d\u86cb\u767d\u7d50\u5408\u578b\u7d2b\u6749\u9187\u5316\u7642\u85e5\uff08nab-paclitaxel\uff09\uff1b\u53e6\u4e00\u7d44\u9664\u63a1\u7528nab-paclitaxel\u4ee5\u5916\uff0c\u9084\u52a0\u5165\u514d\u75ab\u6cbb\u7642\u85e5\u963f\u7279\u73e0\u55ae\u6297\uff08Atezolizumab\uff09\u3002\u7d50\u679c\u986f\u793a\uff0c\u5728\u514d\u75ab\u6aa2\u67e5\u9edePD-L1\u967d\u6027\u60a3\u8005\u4e2d\uff0c\u514d\u75ab\u6cbb\u7642\u85e5Atezolizumab\u914d\u642d\u5316\u7642\u85e5nab-paclitaxel\uff0c\u6bd4\u8d77\u55ae\u7528nab-paclitaxel\uff0c\u66f4\u80fd\u986f\u8457\u964d\u4f4e\u75be\u75c5\u60e1\u5316\u7684\u98a8\u96aa\u3002\u60a3\u8005\u7684\u7121\u60e1\u5316\u751f\u5b58\u4e2d\u4f4d\u6578\u75315.0\u500b\u6708\u5ef6\u9577\u81f37.5\u500b\u6708\uff0c\u6574\u9ad4\u5b58\u6d3b\u671f\u4e2d\u4f4d\u6578\u5247\u753118\u500b\u6708\u5ef6\u9577\u81f325\u500b\u6708\u3002\u800c\u4e14\u5169\u7a2e\u85e5\u7269\u914d\u642d\u7684\u8010\u53d7\u6027\u826f\u597d\uff0c\u85e5\u7269\u6574\u9ad4\u5b89\u5168\u7a0b\u5ea6\u4e5f\u548c\u5316\u7642\u6c92\u6709\u5f88\u5927\u6539\u8b8a\u3002<\/p>\n<p>\u53e6\u4e00\u9805\u6709\u95dc\u514d\u75ab\u6cbb\u7642\u85e5\u7269\u7528\u65bc\u624b\u8853\u524d\u6cbb\u7642\u7684\u7814\u7a76\uff0c\u5229\u7528\u514d\u75ab\u6cbb\u7642\u85e5\u7269\u6d3e\u59c6\u55ae\u6297\uff08Pembrolizumab\uff09\u914d\u5408\u624b\u8853\u524d\u5316\u7642\uff0c\u6216\u55ae\u7528\u6d3e\u59c6\u55ae\u6297\uff0c\u8207\u624b\u8853\u524d\u5316\u7642\u4f5c\u5c0d\u6bd4\u3002\u7814\u7a76\u6536\u9304\u4e861174\u540d\u4e09\u9670\u6027\u4e73\u764c\u60a3\u8005\uff0c\u767c\u73fe\u6d3e\u59c6\u55ae\u6297\u914d\u5408\u5316\u7642\u80fd\u589e\u52a0\u75c5\u7406\u5b78\u5b8c\u5168\u53cd\u61c9 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