{"id":16360,"date":"2024-08-22T16:59:25","date_gmt":"2024-08-22T08:59:25","guid":{"rendered":"\/\/www.afterroberto.com\/?p=16360"},"modified":"2024-08-22T16:59:27","modified_gmt":"2024-08-22T08:59:27","slug":"%e6%88%aa%e6%93%8a%e8%b6%85%e6%83%a1%e8%83%b0%e8%87%9f%e7%99%8c-%e9%ab%98%e5%8d%b1%e6%97%8f%e9%a9%97%e5%ae%9a%e5%9f%ba%e5%9b%a0-%e5%85%a9%e8%bf%91%e8%a6%aa%e7%a2%ba%e8%a8%ba-%e5%ae%b6%e4%ba%ba","status":"publish","type":"post","link":"\/\/www.afterroberto.com\/%e6%88%aa%e6%93%8a%e8%b6%85%e6%83%a1%e8%83%b0%e8%87%9f%e7%99%8c-%e9%ab%98%e5%8d%b1%e6%97%8f%e9%a9%97%e5%ae%9a%e5%9f%ba%e5%9b%a0-%e5%85%a9%e8%bf%91%e8%a6%aa%e7%a2%ba%e8%a8%ba-%e5%ae%b6%e4%ba%ba\/","title":{"rendered":"\u80f0\u81df\u764c | \u6b7b\u4ea1\u7387\u9ad8\uff1f\u80f0\u81df\u764c\u75c5\u5fb5\u3001\u5f15\u81f4\u57fa\u56e0\u7a81\u8b8a5\u5927\u9ad8\u5371\u56e0\u7d20 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href=\"https:\/\/www3.ha.org.hk\/cancereg\/tc\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc3<\/a>2018\u5e74\u5341\u5927\u764c\u75c7\u6b7b\u4ea1\u6578\u5b57\u986f\u793a\uff0c\u80f0\u81df\u764c\u6392\u7b2c\u4e94\uff0c\u596a\u53bb\u4e86711\u4eba\u7684\u6027\u547d\u3002\u80f0\u81df\u764c\u4e94\u5e74\u5b58\u6d3b\u73875%\u81f38%\uff0c\u70ba\u6240\u6709\u4e3b\u8981\u764c\u75c7\u4e2d\u6700\u4f4e\u3002\u5927\u90e8\u5206\u60a3\u8005\u767c\u73fe\u6642\u5df2\u5c46\u4e2d\u665a\u671f\uff0c\u53ea\u6709\u7d0420%\u7684\u75c5\u4eba\u9069\u5408\u52d5\u624b\u8853\u4f5c\u6839\u6cbb\u6027\u5207\u9664\uff0c\u5176\u9918\u60a3\u8005\u6cbb\u7642\u4ee5\u5316\u7642\u70ba\u4e3b\u3002\u7a76\u7adf\u80f0\u81df\u764c\u7684\u5177\u9ad4\u6210\u56e0\u662f\u4ec0\u9ebc\uff1f\u6709\u54ea\u4e9b\u5f15\u81f4\u57fa\u56e0\u7a81\u8b8a\u7684\u9ad8\u5371\u56e0\u7d20\u5462\uff1f\u54ea\u985e\u4eba\u58eb\u662f\u9ad8\u5371\u4e00\u65cf\u5b9c\u63d0\u9ad8\u8b66\u89ba\u5462\uff1f<\/p>\n\n\n\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-full wp-image-16362\" src=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-1.jpg\" alt=\"\u80f0\u81df\u764c,\u764c\u75c7,\u907a\u50b3,\u57fa\u56e0\u7a81\u8b8a,\u5438\u7159,\u9157\u9152,\u80a5\u80d6,\u6162\u6027\u80f0\u81df\u708e,\u907a\u50b3\u6027\u816b\u7624\u7d9c\u5408\u75c7,\u5bb6\u65cf\u6027\u80f0\u81df\u764c,\u907a\u50b3\u6027\u4e73\u764c,\u5375\u5de2\u764c\u75c7\u5019\u7fa4,\u57fa\u56e0\u6e2c\u8a66,\" width=\"822\" height=\"522\" title=\"\" srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-1.jpg 822w, \/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-1-300x191.jpg 300w, \/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-1-150x95.jpg 150w, \/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-1-768x488.jpg 768w, \/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-1-250x159.jpg 250w\" sizes=\"(max-width: 822px) 100vw, 822px\" \/><br><span class=\"caption\">\u4e0a\u5347\u8da8\u52e2\u2014\u2014\u80f0\u81df\u764c\u6709\u6309\u5e74\u4e0a\u5347\u7684\u8da8\u52e2\uff0c\u75312008\u5e74\u7684448\u5b97\u65b0\u75c7\u500b\u6848\u5347\u81f32016\u5e74\u7684702\u5b97\uff0c\u800c\u6839\u64da\u897f\u65b9\u570b\u5bb6\u7d93\u9a57\uff0c\u80f0\u81df\u764c\u500b\u6848\u4ecd\u6703\u9032\u4e00\u6b65\u4e0a\u5347\u3002\uff08Eraxion@iStockphoto\/\u660e\u5831\u88fd\u5716\uff09<\/span><\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u80f0\u81df\u764c\u6210\u56e0\u4e0d\u660e\u3000\u5f15\u81f4\u57fa\u56e0\u7a81\u8b8a\u9ad8\u5371\u56e0\u7d20<\/h2>\n\n\n\n<p>\u80f0\u81df\u764c\u7684\u5177\u9ad4\u6210\u56e0\u4e0d\u5b8c\u5168\u6e05\u695a\u3002\u5927\u90e8\u5206\u500b\u6848\u70ba\u57fa\u56e0\u5f8c\u5929\u5076\u767c\u7a81\u8b8a\uff08sporadic\uff09\u5f15\u8d77\uff0c\u5f15\u81f4\u57fa\u56e0\u7a81\u8b8a\u7684\u9ad8\u5371\u56e0\u7d20\u5305\u62ec\uff1a\u5438\u7159\u3001\u9157\u9152\u3001\u80a5\u80d6\u3001\u7f3a\u4e4f\u904b\u52d5\u3001\u6162\u6027\u80f0\u81df\u708e\u7b49\u3002\u6309\u897f\u65b9\u570b\u5bb6\u7684\u7814\u7a76\uff0c\u7d0410%\u81f315%\u80f0\u81df\u764c\u500b\u6848\u6709\u907a\u50b3\uff08genetic\uff09\u56e0\u7d20\uff0c\u7576\u4e2d\u53c8\u53ef\u518d\u5206\u70ba\u5169\u985e\uff1a<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u5bb6\u65cf\u6027\u80f0\u81df\u764c\uff08Familial pancreatic cancer\uff09<\/strong><br>\u5bb6\u65cf\u4e2d\u6709\u6700\u5c11\u5169\u540d\u8fd1\u89aa\uff08\u5144\u5f1f\u59ca\u59b9\u3001\u7236\u6bcd\u6216\u5b50\u5973\uff09\u78ba\u8a3a\u7f79\u60a3\u80f0\u81df\u764c\uff0c\u800c\u672c\u8eab\u975e\u907a\u50b3\u6027\u816b\u7624\u7d9c\u5408\u75c7\u60a3\u8005\uff0c\u4fbf\u5c6c\u5bb6\u65cf\u6027\u80f0\u81df\u764c\u3002\u6839\u64da\u7d71\u8a08\uff0c\u82e5\u6709\u4e00\u500b\u8fd1\u89aa\u7f79\u60a3\u80f0\u81df\u764c\uff0c\u5176\u9918\u5bb6\u65cf\u6210\u54e1\u7684\u7f79\u60a3\u98a8\u96aa\u6703\u6bd4\u4e00\u822c\u4eba\u9ad8\u51fa3\u81f35\u500d\uff1b\u6709\u5169\u500b\u8fd1\u89aa\u7f79\u60a3\u80f0\u81df\u764c\uff0c\u98a8\u96aa\u6bd4\u5e38\u4eba\u9ad85\u81f37\u500d\uff1b\u4e09\u500b\u8fd1\u89aa\u7f79\u60a3\u80f0\u81df\u764c\uff0c\u98a8\u96aa\u9ad830\u500d\u3002<\/li>\n\n\n\n<li><strong>\u907a\u50b3\u6027\u816b\u7624\u7d9c\u5408\u75c7\uff08Hereditary Cancer Syndrome\uff09<\/strong><br>\u6211\u5011\u8207\u751f\u4ff1\u4f86\u64c1\u6709\u7d043\u842c\u7d44\u57fa\u56e0\uff0c\u6bcf\u7d44\u57fa\u56e0\u6709\u4e00\u5c0d\uff0c\u4e00\u500b\u5f9e\u7236\u89aa\u907a\u50b3\uff0c\u4e00\u500b\u5f9e\u6bcd\u89aa\u907a\u50b3\u3002\u7576\u4e2d\u5c0f\u90e8\u5206\u7684\u57fa\u56e0\u5c0d\u6291\u5236\u6216\u4fc3\u9032\u764c\u75c7\u5f62\u6210\u8d77\u95dc\u9375\u4f5c\u7528\u3002\u907a\u50b3\u6027\u816b\u7624\u7d9c\u5408\u75c7\u60a3\u8005\uff0c\u5176\u6291\u5236\u6216\u4fc3\u9032\u764c\u75c7\u7684\u57fa\u56e0\u5e36\u6709\u5148\u5929\u7f3a\u9677\uff08Germline mutation\uff09\uff0c\u4e5f\u5c31\u662f\u8aaa\u5728\u4e00\u5c0d\u67d3\u8272\u9ad4\u4e2d\uff0c\u5176\u4e2d\u4e00\u689d\u57fa\u56e0\u5929\u751f\u4fbf\u6709\u7f3a\u9677\uff0c\u7576\u4eba\u9ad4\u5728\u751f\u9577\u904e\u7a0b\u4e2d\uff0c\u56e0\u74b0\u5883\u6216\u5176\u4ed6\u56e0\u7d20\uff0c\u53e6\u4e00\u689d\u57fa\u56e0\u4ea6\u767c\u751f\u8b8a\u7570\u6642\uff0c\u7d30\u80de\u4fbf\u5bb9\u6613\u4e0d\u53d7\u63a7\u5236\uff0c\u5927\u5927\u589e\u52a0\u60a3\u764c\u98a8\u96aa\uff1b\u800c\u7236\u6bcd\u6709\u7f3a\u9677\u7684\u57fa\u56e0\u4ea6\u6709\u53ef\u80fd\u50b3\u7d66\u4e0b\u4e00\u4ee3\u3002<\/li>\n<\/ol>\n\n\n\n<p><img decoding=\"async\" src=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-4.jpg\" alt=\"\u80f0\u81df\u764c,\u764c\u75c7,\u907a\u50b3,\u57fa\u56e0\u7a81\u8b8a,\u5438\u7159,\u9157\u9152,\u80a5\u80d6,\u6162\u6027\u80f0\u81df\u708e,\u907a\u50b3\u6027\u816b\u7624\u7d9c\u5408\u75c7,\u5bb6\u65cf\u6027\u80f0\u81df\u764c,\u907a\u50b3\u6027\u4e73\u764c,\u5375\u5de2\u764c\u75c7\u5019\u7fa4,\u57fa\u56e0\u6e2c\u8a66,\" title=\"\"><br><span class=\"caption\">\uff08\u660e\u5831\u88fd\u5716\uff09<\/span><\/p>\n\n\n\n<p>\u5728\u773e\u591a\u8207\u80f0\u81df\u764c\u6709\u95dc\u7684\u907a\u50b3\u6027\u816b\u7624\u7d9c\u5408\u75c7\uff0c\u5176\u4e2d\u4ee5\u907a\u50b3\u6027\u4e73\u764c\u8207\u5375\u5de2\u764c\u75c7\u5019\u7fa4\uff08Hereditary breast and ovarian cancer syndrome\uff09\u8f03\u70ba\u666e\u904d\u3002\u6b64\u764c\u75c7\u5019\u7fa4\u6e90\u81eaBRCA1\u6216BRCA2\u57fa\u56e0\u8b8a\u7570\uff0c\u9019\u5169\u500b\u57fa\u56e0\u7686\u5c6c\u6291\u764c\u57fa\u56e0\uff08Tumor-suppressor gene\uff09\uff0c\u8ca0\u8cac\u4fee\u5fa9\u640d\u58de\u7684DNA\u3002\u56e0\u6b64\uff0c\u7576BRCA\u57fa\u56e0\u767c\u751f\u7f3a\u9677\uff0cDNA\u53d7\u5230\u653b\u64ca\u800c\u65b7\u88c2\u7834\u58de\u5f8c\u6703\u7121\u6cd5\u6b63\u78ba\u4fee\u5fa9\uff0c\u7d30\u80de\u5167DNA\u640d\u58de\u7d2f\u7a4d\u5230\u4e00\u5b9a\u7a0b\u5ea6\uff0c\u7d30\u80de\u5c31\u6703\u767c\u751f\u764c\u8b8a\u3002<br><br>BRCA\u57fa\u56e0\u8207\u4e73\u764c\u53ca\u5375\u5de2\u764c\u7684\u95dc\u806f\uff0c\u56e0\u8377\u674e\u6d3b\u5973\u661f\u5b89\u7956\u84ee\u5a1c\u7956\u8389\u63a5\u53d7\u9810\u9632\u6027\u96d9\u4e73\u623f\u5207\u9664\u624b\u8853\u800c\u5ee3\u70ba\u4eba\u77e5\u3002\u5e36\u6709BRCA\u57fa\u56e0\u7a81\u8b8a\u7684\u4eba\uff0c\u7d42\u5176\u4e00\u751f\u60a3\u4e0a\u4e73\u764c\u7684\u98a8\u96aa\u9ad8\u9054\u7d0440%\u81f387%\uff0c\u5375\u5de2\u764c\u7d0416%\u81f360%\uff0c\u767c\u75c5\u5e74\u9f61\u4ea6\u6703\u8f03\u4e00\u822c\u4eba\u5e74\u8f15\u3002\u81f3\u65bc\u80f0\u81df\u764c\uff0c\u6108\u4f86\u6108\u591a\u6578\u64da\u986f\u793aBRCA\u57fa\u56e0\u7a81\u8b8a\u8005\u60a3\u80f0\u81df\u764c\u7684\u98a8\u96aa\u4ea6\u6703\u589e\u52a0\uff0c\u5927\u578b\u7814\u7a76\u986f\u793a\u60a3\u80f0\u81df\u764c\u98a8\u96aa\u6bd4\u5e38\u4eba\u9ad8\u51fa\u5169\u500d\uff1b\u4f46\u6709\u5225\u65bc\u4e73\u764c\u53ca\u5375\u5de2\u764c\uff0cBRCA\u76f8\u95dc\u7684\u80f0\u81df\u764c\u7684\u767c\u75c5\u5e74\u9f61\u8207\u5176\u4ed6\u80f0\u81df\u764c\u60a3\u8005\u7121\u7570\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-cyan-bluish-gray-color has-alpha-channel-opacity has-cyan-bluish-gray-background-color has-background is-style-wide\"\/>\n\n\n\n<p><\/p>\n\n\n\n<p>\u76f8\u95dc\u6587\u7ae0\uff1a<a href=\"\/\/www.afterroberto.com\/%e8%83%b0%e8%87%9f%e7%99%8c%e6%ad%bb%e4%ba%a1%e7%8e%87%e8%bf%91%e4%b9%9d%e6%88%90-%e6%b0%b4%e7%98%a4%e8%bf%91%e5%8d%8a%e8%ae%8a%e7%99%8c-%e3%80%8c%e8%83%83%e7%97%9b%e3%80%8d%e8%a6%81%e7%95%99%e7%a5%9e\/\">\u80f0\u81df\u764c\u75c5\u5fb5\uff1a\u9ad4\u91cd\u4e0b\u964d\u986f\u8457 \u75c5\u4eba\u63a5\u53d7\u60e0\u666e\u723e\u624b\u8853\u5f8c\u6d88\u5316\u529f\u80fd\u53d7\u640d \u98f2\u98df\u6709\u5c0d\u7b56<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-cyan-bluish-gray-color has-alpha-channel-opacity has-cyan-bluish-gray-background-color has-background is-style-wide\"\/>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u53ca\u65e9\u767c\u73fe\u6216\u53ef\u4f5c\u624b\u8853 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ultrasound\uff09\u53ca\u78c1\u529b\u5171\u632f\uff08MRI\uff09\u6aa2\u67e5\uff0c\u4ee5\u7b56\u842c\u5168\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter wp-image-16363 size-full\"><img decoding=\"async\" width=\"473\" height=\"405\" src=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-2.jpg\" alt=\"\u80f0\u81df\u764c,\u764c\u75c7,\u907a\u50b3,\u57fa\u56e0\u7a81\u8b8a,\u5438\u7159,\u9157\u9152,\u80a5\u80d6,\u6162\u6027\u80f0\u81df\u708e,\u907a\u50b3\u6027\u816b\u7624\u7d9c\u5408\u75c7,\u5bb6\u65cf\u6027\u80f0\u81df\u764c,\u907a\u50b3\u6027\u4e73\u764c,\u5375\u5de2\u764c\u75c7\u5019\u7fa4,\u57fa\u56e0\u6e2c\u8a66,\" class=\"wp-image-16363\" title=\"\" srcset=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-2.jpg 473w, \/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-2-150x128.jpg 150w, \/\/www.afterroberto.com\/wp-content\/uploads\/2019\/01\/health-0114-pancreas-2-300x257.jpg 300w\" sizes=\"(max-width: 473px) 100vw, 473px\" \/><figcaption class=\"wp-element-caption\">\u907a\u50b3\u56e0\u7d20\u2014\u2014\u7d0410%\u81f315%\u80f0\u81df\u764c\u500b\u6848\u6709\u907a\u50b3\u56e0\u7d20\uff0c\u73fe\u6642\u79d1\u6280\u5df2\u53ef\u900f\u904e\u9a57\u8840\u627e\u51fa\u554f\u984c\u57fa\u56e0\uff0c\u5e6b\u52a9\u91ab\u751f\u627e\u51fa\u5c0d\u61c9\u9810\u9632\u548c\u6cbb\u7642\u65b9\u6848\u3002\uff08Ca-ssis@iStockphoto\uff09<\/figcaption><\/figure>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u80f0\u81df\u764c7\u985e\u9ad8\u5371\u4e00\u65cf<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5bb6\u65cf\u4e2d\u6709\u6700\u5c11\u5169\u540d\u8fd1\u89aa\u78ba\u8a3a\u7f79\u60a3\u80f0\u81df\u764c<\/li>\n\n\n\n<li>\u5e36\u6709\u5148\u5929\u6027\u57fa\u56e0\u7f3a\u9677\u7684\u907a\u50b3\u6027\u816b\u7624\u7d9c\u5408\u75c7\u60a3\u8005\uff1a<\/li>\n\n\n\n<li>BRCA\u3001PALB2\uff1a\u907a\u50b3\u6027\u4e73\u764c\u8207\u5375\u5de2\u764c\u75c7\u5019\u7fa4\uff08Hereditary breast and ovarian cancer syndrome\uff09<\/li>\n\n\n\n<li>CDKN2A\uff1a\u5bb6\u65cf\u6027\u975e\u5178\u578b\u6027\u591a\u75e3\u548c\u9ed1\u8272\u7d20\u7624\u75c7\u5019\u7fa4\uff08Familial atypical multiple mole melanoma\uff09<\/li>\n\n\n\n<li>\u932f\u914d\u4fee\u88dc\u57fa\u56e0\uff08Mismatch Repair genes\u3001MMR\u57fa\u56e0\uff09 MLH1\u3001MSH2\u3001MSH6\u3001PMS2\uff1a\u9023\u6c0f\u7d9c\u5408\u75c7\uff08Lynch syndrome\uff09\uff0c\u820a\u7a31\u907a\u50b3\u6027\u975e\u761c\u8089\u7d50\u76f4\u8178\u764c\u75c7\u5019\u7fa4<\/li>\n\n\n\n<li>STK11\uff1a\u9ed1\u6591\u606f\u8089\u75c7\u5019\u7fa4\uff08Peutz-Jeghers syndrome\uff09<\/li>\n\n\n\n<li>PRSS1\uff1a\u907a\u50b3\u6027\u80f0\u817a\u708e\uff08Hereditary Pancreatitis\uff09\u7b49<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u80f0\u81df\u764c6\u500b\u5fb5\u72c0<\/h2>\n\n\n\n<p>\u81f3\u65bc\u80f0\u81df\u764c\u65e9\u671f\u75c5\u5fb5\u4e26\u4e0d\u660e\u986f\uff0c\u64da\u667a\u53cb\u7ad9\u8cc7\u6599\u986f\u793a\uff0c\u8f03\u5e38\u898b\u7684\u75c5\u5fb5\u5305\u62ec\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u4e0a\u8179\u90e8\u51fa\u73fe\u8207\u98f2\u98df\u7121\u95dc\u7684\u6301\u7e8c\u75bc\u75db, \u4e26\u6703\u53cd\u5c04\u81f3\u80cc\u90e8<\/li>\n\n\n\n<li>\u98df\u617e\u4e0d\u632f\u3001\u5641\u5fc3\u3001\u5614\u5410\u3001\u6d88\u5316\u4e0d\u826f\u3001\u8179\u8139\u7b49\u8178\u80c3\u969c\u7919\u73fe\u8c61<\/li>\n\n\n\n<li>\u51fa\u73fe\u9ec3\u75b8\u3001\u76ae\u819a\u6414\u7662\u3001\u5927\u4fbf\u5448\u9676\u571f\u8272<\/li>\n\n\n\n<li>\u9ad4\u91cd\u77ed\u6642\u9593\u5167\u92b3\u6e1b<\/li>\n\n\n\n<li>\u4e0a\u8179\u90e8\u51fa\u73fe\u56fa\u5b9a\u3001\u5805\u786c\u7684\u816b\u584a<\/li>\n\n\n\n<li>\u8179\u6c34<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u57fa\u56e0\u6e2c\u8a66 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