{"id":12826,"date":"2018-04-02T17:48:01","date_gmt":"2018-04-02T09:48:01","guid":{"rendered":"\/\/www.afterroberto.com\/?p=12826"},"modified":"2019-06-20T16:32:34","modified_gmt":"2019-06-20T08:32:34","slug":"%e6%96%b0%e9%9b%bb%e7%99%82%e9%9a%94%e5%b1%b1%e6%89%93%e7%89%9b-%e6%bf%80%e6%b4%bb%e5%85%8d%e7%96%ab%e7%b3%bb%e7%b5%b1%e6%8a%97%e7%99%8c","status":"publish","type":"post","link":"\/\/www.afterroberto.com\/%e6%96%b0%e9%9b%bb%e7%99%82%e9%9a%94%e5%b1%b1%e6%89%93%e7%89%9b-%e6%bf%80%e6%b4%bb%e5%85%8d%e7%96%ab%e7%b3%bb%e7%b5%b1%e6%8a%97%e7%99%8c\/","title":{"rendered":"\u3010\u809d\u708e\u8207\u809d\u764c\u3011\u65b0\u96fb\u7642\u9694\u5c71\u6253\u725b \u6fc0\u6d3b\u514d\u75ab\u7cfb\u7d71\u6297\u764c"},"content":{"rendered":"<p>\u3010\u660e\u5831\u5c08\u8a0a\u3011\u764c\u75c7\u7814\u7a76\u65b0\u65b9\u5411\uff1a\u7acb\u9ad4\u5b9a\u4f4d\u653e\u5c04\u6cbb\u7642\u8207\u514d\u75ab\u6cbb\u7642\u7d50\u5408\u61c9\u7528\uff08combined SBRT and 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1\uff09\u662f\u514d\u75ab\u7d30\u80de\u8868\u9762\u7684\u86cb\u767d\u8cea\uff0c\u8ca0\u8cac\u8abf\u7bc0\u514d\u75ab\u7cfb\u7d71\u529f\u80fd\uff0c\u4ee4\u6574\u500b\u514d\u75ab\u7cfb\u7d71\u6070\u5982\u5176\u5206\u904b\u4f5c\u3002\u7136\u800c\u7576\u764c\u7d30\u80de\u8868\u9762\u7684PD-L1\u914d\u9ad4\uff0c\u8207\u514d\u75ab\u7d30\u80de\u7684PD-1\u7d50\u5408\uff0c\u4fbf\u6703\u6291\u5236\u4e86\u514d\u75ab\u7d30\u80de\u7684\u6bba\u6ec5\u80fd\u529b\uff1b\u60c5\u51b5\u604d\u5982\u764c\u7d30\u80de\u55ac\u88dd\u6210\u6b63\u5e38\u7d30\u80de\uff0c\u907f\u904e\u514d\u75ab\u7d30\u80de\u7684\u76e3\u5bdf\u3002\u800c\u514d\u75ab\u6aa2\u67e5\u7ad9\uff08PD-1\uff09\u6291\u5236\u5291\u7684\u4f5c\u7528\u4fbf\u662f\u9ecf\u5728\u514d\u75ab\u7d30\u80dePD-1\u4e4b\u4e0a\uff0c\u50cf\u4fdd\u8b77\u7f69\u822c\u963b\u6b62\u764c\u7d30\u80de\u7684PD-L1\u914d\u9ad4\u8207PD-1\u63a5\u89f8\uff0c\u4ee4\u514d\u75ab\u7d30\u80de\u4e0d\u518d\u53d7\u764c\u7d30\u80de\u6240\u6b3a\u9a19\uff0c\u91cb\u653e\u5176\u539f\u6709\u6297\u764c\u80fd\u529b\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u80ba\u3001\u814e\u3001\u8180\u80f1\u7b49\u764c\u75c7\u9069\u7528<\/h2>\n<p>\u81e8\u7240\u7814\u7a76\u5df2\u8b49\u5be6\u514d\u75ab\u6aa2\u67e5\u7ad9\u6291\u5236\u5291\u53ef\u7528\u65bc\u6cbb\u7642\u9ed1\u8272\u7d20\u7624\u3001\u80ba\u764c\u3001\u814e\u764c\u3001\u8180\u80f1\u764c\u3001\u982d\u9838\u764c\u7b49\u764c\u75c7\uff0c\u4f46\u6b64\u7642\u6cd5\u4e26\u975e\u9069\u7528\u65bc\u6240\u6709\u764c\u75c7\u60a3\u8005\uff0c\u800c\u4e14\u4e26\u975e\u6c92\u6709\u526f\u4f5c\u7528\uff0c\u5e38\u898b\u7684\u526f\u4f5c\u7528\u5305\u62ec\uff1a\u75b2\u5026\u3001\u8179\u7009\u3001\u76ae\u75b9\/\u75d5\u7662\u3001\u98df\u617e\u4e0d\u632f\u53ca\u808c\u8089\u75bc\u75db\uff1b\u800c\u7f55\u898b\u7684\u56b4\u91cd\u526f\u4f5c\u7528\u5305\u62ec\u7531\u514d\u75ab\u7cfb\u7d71\u5931\u8abf\u5f15\u8d77\u7684\u80ba\u708e\u3001\u8178\u708e\u3001\u809d\u708e\u53ca\u5167\u5206\u6ccc\u5931\u8abf\u7b49\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u7cbe\u6e96\u6253\u764c\u300c\u9806\u4fbf\u300d\u523a\u6fc0\u514d\u75ab\u5927\u8ecd<\/h2>\n<p>\u50b3\u7d71\u653e\u5c04\u6cbb\u7642\uff08\u96fb\u7642\uff09\u6bba\u6b7b\u9aa8\u9ad3\u53ca\u8840\u6db2\u4e2d\u7684\u514d\u75ab\u7d30\u80de\uff0c\u5c0d\u81ea\u8eab\u514d\u75ab\u7cfb\u7d71\u6709\u6291\u5236\u4f5c\u7528\u3002\u4f46\u8fd1\u5e74\u7814\u7a76\u767c\u73fe\uff0c\u65b0\u7684\u7acb\u9ad4\u5b9a\u4f4d\u653e\u5c04\u96fb\u7642\uff08SBRT\uff09 \uff08\u8a3b\uff09\uff0c\u6709\u523a\u6fc0\u514d\u75ab\u7cfb\u7d71\u7684\u6548\u679c\uff0c\u4e3b\u56e0\u6709\u4e8c\uff0c\u9996\u5148\u662fSBRT\u900f\u904e\u5f71\u50cf\u5c0e\u822a\uff08image-guidance\uff09\u6280\u8853\u80fd\u7cbe\u6e96\u6253\u64ca\u816b\u7624\uff0c\u6e1b\u5c11\u5c0d\u9aa8\u9ad3\u53ca\u8840\u6db2\u7b49\u514d\u75ab\u7cfb\u7d71\u7684\u7834\u58de\uff1b\u5176\u6b21\u662f\u7531\u65bcSBRT\u7528\u9ad8\u5291\u91cf\u7684\u8f3b\u5c04\u6253\u64ca\u816b\u7624\uff0c\u904e\u7a0b\u4e2d\u6703\u88fd\u9020\u5927\u91cf\u7684\u816b\u7624\u6b98\u6e23\uff0c\u5f9e\u800c\u523a\u6fc0\u514d\u75ab\u7cfb\u7d71\u91cb\u653e\u5927\u91cf\u514d\u75ab\u7d30\u80de\uff0c\u4e26\u52a0\u5f37\u60a3\u8005\u514d\u75ab\u7d30\u80de\u5c0d\u764c\u7d30\u80de\u7684\u8fa8\u8a8d\u80fd\u529b\u3002<\/p>\n<p>\u76f8\u4fe1\u8070\u660e\u7684\u8b80\u8005\u5fc5\u5b9a\u6703\u554f\uff0c\u65e2\u7136\u514d\u75ab\u7642\u6cd5\u53ca\u96fb\u7642\u5747\u80fd\u523a\u6fc0\u60a3\u8005\u7684\u514d\u75ab\u7cfb\u7d71\uff0c\u5169\u8005\u80fd\u5426\u96d9\u528d\u5408\u74a7\uff0c\u651c\u624b\u5c0d\u6297\u764c\u9b54\u5462\uff1f<\/p>\n<p>&nbsp;<\/p>\n<h2>\u96fb\u7642\u300c\u9060\u9694\u6548\u61c9\u300d\u3000\u8ffd\u8e64\u9060\u8655\u816b\u7624<\/h2>\n<p>\u5927\u91cf\u57fa\u790e\u7814\u7a76\u8b49\u5be6\uff0c\u96fb\u7642\u80fd\u8207\u514d\u75ab\u6cbb\u7642\u7522\u751f\u5354\u540c\u6548\u61c9\u3002\u50b3\u7d71\u4e0a\u8a8d\u70ba\u96fb\u7642\u662f\u5c40\u90e8\u6cbb\u7642\uff0c\u900f\u904e\u8f3b\u5c04\u7834\u58de\u764c\u7d30\u80de\u7684DNA\u4ee5\u6ec5\u764c\uff0c\u4f46\u6548\u679c\u53ea\u80fd\u91dd\u5c0d\u8f3b\u5c04\u7dda\u7684\u7167\u5c04\u8655\uff1b\u7136\u800c\uff0c\u96fb\u7642\u53e6\u4e00\u7a2e\u6bba\u764c\u7684\u65b9\u5f0f\u537b\u8f03\u5c11\u4eba\u63d0\u53ca\uff0c\u53eb\u4f5c\u9060\u9694\u6548\u61c9\uff08Abscopal effect\uff09\uff0c\u82e5\u5957\u7528\u6210\u8a9e\uff0c\u5c31\u662f\u9694\u5c71\u6253\u725b\u3002\u7c21\u800c\u8a00\u4e4b\uff0c\u6709\u9060\u8655\u64f4\u6563\u7684\u60a3\u8005\uff0c\u63a5\u53d7\u4e86\u539f\u767c\u816b\u7624\u7684\u5c40\u90e8\u653e\u5c04\u6cbb\u7642\u5f8c\uff0c\u4e0d\u55ae\u6cbb\u7642\u8655\u816b\u7624\u6d88\u878d\uff0c\u90a3\u4e9b\u6c92\u6709\u76f4\u63a5\u6cbb\u7642\u7684\u9060\u7aef\u816b\u7624\u4e5f\u6703\u8ddf\u7740\u7e2e\u5c0f\u6216\u6d88\u5931\u3002\u80cc\u5f8c\u539f\u7406\u662f\u96fb\u7642\u80fd\u523a\u6fc0\u514d\u75ab\u7cfb\u7d71\uff0c\u91cb\u653e\u514d\u75ab\u7d30\u80de\u53bb\u8ffd\u8e64\u64b2\u6bba\u9060\u8655\u7684\u764c\u816b\u3002\u9060\u9694\u6548\u61c9\u672c\u975e\u653e\u5c04\u6cbb\u7642\u7684\u4e3b\u6d41\uff0c\u4f46\u8fd1\u5e74\u96a8\u514d\u75ab\u6cbb\u7642\u5927\u884c\u5176\u9053\uff0c\u91cd\u65b0\u6210\u70ba\u816b\u7624\u754c\u611f\u8208\u8da3\u7684\u8a71\u984c\uff0c\u5b83\u7684\u6210\u6548\u5728\u9ed1\u8272\u7d20\u7624\u4e2d\u6548\u679c\u6700\u986f\u8457\uff0c\u800c\u814e\u7d30\u80de\u764c\u3001\u80ba\u764c\u4e5f\u76f8\u7e7c\u6709\u5831\u544a\u9762\u4e16\u3002\u5c0d\u65bc\u514d\u75ab\u6cbb\u7642\u6548\u679c\u6108\u986f\u8457\u7684\u816b\u7624\uff0c\u5176\u5728\u63a5\u53d7\u653e\u5c04\u6cbb\u7642\u6642\u51fa\u73fe\u9060\u9694\u6548\u61c9\u7684\u6a5f\u6703\u5c31\u6108\u9ad8\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" title=\"\u7d50\u5408\u6cbb\u7642\" src=\"\/\/www.afterroberto.com\/wp-content\/uploads\/2018\/04\/02-4.jpg\" alt=\"\u809d\u708e\u8207\u809d\u764c\" \/><br \/>\n<span class=\"caption\">\uff08\u4f5c\u8005\u63d0\u4f9b\uff09<\/span><\/p>\n<p>\u7d50\u5408\u6cbb\u7642\u2014\u2014\u63a5\u53d7\u96fb\u7642\u53ca\u514d\u75ab\u7642\u6cd5\u5f8c\uff0c\u75c5\u4eba\u7684\u809d\u81df\u816b\u7624\uff08\u7d05\u5708\uff09\u5927\u5e45\u7e2e\u5c0f\uff0c\u4f46\u7531\u65bc\u9019\u7a2e\u7d50\u5408\u7642\u6cd5\u4ecd\u5c6c\u7814\u7a76\u968e\u6bb5\uff0c\u4ecd\u9700\u9032\u4e00\u6b65\u63a2\u8a0e\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u7814\u7a76\u986f\u793a\u3000\u5b58\u6d3b\u671f\u5ef6\u9577\u903e\u500d<\/h2>\n<p>\u53bb\u5e74\u65b0\u82f1\u683c\u862d\u91ab\u5b78\u96dc\u8a8cNew England Journal of Medicine\u767c\u8868\u7684\u5927\u578b\u7814\u7a76Pacific Trial\uff0c\u7814\u7a76\u5c0d\u8c61\u70ba\u7b2c3\u671f\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\u3002\u7814\u7a76\u5c07\u75c5\u4eba\u5206\u6210\u5169\u7d44\uff0c\u5206\u5225\u70ba\u50b3\u7d71\u6cbb\u7642\u6cd5\uff0c\u5373\u96fb\u7642\u548c\u5316\u7642\uff1b\u53e6\u4e00\u7d44\u662f\u96fb\u7642\u548c\u5316\u7642\u5916\uff0c\u518d\u914d\u5408\u514d\u75ab\u7642\u6cd5\u3002\u7814\u7a76\u986f\u793a\uff0c\u50b3\u7d71\u7d44\u5225\u5b8c\u6210\u7642\u7a0b\u5f8c\uff0c\u60a3\u8005\u7684\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u50c5\u7d045.6\u500b\u6708\uff1b\u800c\u514d\u75ab\u7642\u6cd5\u7d44\u5225\u5247\u5927\u5e45\u63d0\u5347\u81f316.8\u500b\u6708\u3002<\/p>\n<p>\u523a\u91ddLancet Oncology\u540c\u5e74\u4ea6\u6709\u7814\u7a76\u520a\u767b\uff0c\u6307\u51fa\u665a\u671f\u80ba\u764c\u75c5\u4eba\u63a5\u53d7\u514d\u75ab\u6cbb\u7642\u4e4b\u9918\uff0c\u540c\u6642\u63a5\u53d7\u96fb\u7642\u7684\u8a71\uff0c\u6bd4\u8d77\u6c92\u6709\u63a5\u53d7\u96fb\u7642\u7684\u5c0d\u7167\u7d44\uff0c\u5176\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u53ca\u5e73\u5747\u58fd\u547d\u4ea6\u986f\u8457\u5ef6\u9577\u3002\u9019\u4e9b\u7814\u7a76\u7d50\u679c\u90fd\u9593\u63a5\u5f15\u8b49\u4e86\u96fb\u7642\u53ca\u514d\u75ab\u7642\u6cd5\u7684\u5354\u540c\u6548\u61c9\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u5291\u91cf\u3001\u9776\u5340\u5927\u5c0f\u6709\u5f85\u7814\u7a76<\/h2>\n<p>\u9673\u5148\u751f\u5f88\u5e78\u904b\uff0c\u5728\u63a5\u53d7\u904e\u96fb\u7642\u53ca\u514d\u75ab\u7642\u6cd5\u5f8c\uff0c\u809d\u81df\u816b\u7624\u5927\u5e45\u5ea6\u7e2e\u5c0f\uff08\u4e0b\u5716\uff09\uff0c\u7576\u4ed6\u8207\u6211\u5206\u4eab\u4ed6\u5011\u4e00\u5bb6\u6700\u8fd1\u5171\u5ea6\u6625\u7bc0\u7684\u9ede\u6ef4\u6642\uff0c\u7b46\u8005\u4e5f\u5fc3\u5b58\u611f\u6069\u3002\u4f46\u5728\u6b64\u5f37\u8abf\uff0c\u6b64\u5c6c\u500b\u5225\u6848\u4f8b\uff0c\u73fe\u968e\u6bb5SBRT\u8207\u514d\u75ab\u7642\u6cd5\u7684\u7d50\u5408\u61c9\u7528\u4ecd\u5c6c\u7814\u7a76\u968e\u6bb5\uff0c\u5176\u529f\u6548\u53ca\u5b89\u5168\u5ea6\u4ecd\u6709\u5f85\u66f4\u591a\u81e8\u7240\u5be6\u9a57\u53bb\u8b49\u5be6\u3002\u5f88\u591a\u7591\u554f\u5982\uff1a\u7d50\u5408\u6cbb\u7642\u6642\u96fb\u7642\u53ca\u514d\u75ab\u7642\u6cd5\u7684\u5408\u9069\u5291\u91cf\u3001\u96fb\u7642\u9776\u5340\u7684\u5927\u5c0f\uff0c\u6216\u5169\u8005\u5728\u6cbb\u7642\u6642\u9593\u4e0a\u7684\u914d\u5408\u7b49\uff0c\u4ecd\u9700\u9032\u4e00\u6b65\u63a2\u8a0e\u3002\u4f46\u6beb\u7121\u7591\u554f\uff0c\u653e\u5c04\u6cbb\u7642\u8207\u514d\u75ab\u6cbb\u7642\u7d50\u5408\u61c9\u7528\u5c07\u6703\u662f\u764c\u75c7\u7814\u7a76\u4e00\u500b\u91cd\u8981\u65b9\u5411\u3002\u671f\u671b\u66f4\u591a\u7684\u7814\u7a76\u7d50\u679c\u80fd\u8b93\u6b64\u7642\u6cd5\u666e\u53ca\u61c9\u7528\uff0c\u8b93\u66f4\u591a\u75c5\u4eba\u53d7\u60e0\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u6587\uff1a\u8523\u5b50\u6a11\u91ab\u751f\uff08<a href=\"https:\/\/www.hku.hk\/c_index.html\" target=\"_blank\" rel=\"noopener\">\u9999\u6e2f\u5927\u5b78<\/a>\u81e8\u7240\u816b\u7624\u79d1\u81e8\u7240\u52a9\u7406\u6559\u6388\uff09<\/p>\n<section class=\"widget_featured_posts\" style=\"margin-top: 50px;\">\n<h3 class=\"widget-title\" style=\"font-size: 23px; color: #188073;\">\u809d\u708e\u8207\u809d\u764c\u7cfb\u5217\u6587\u7ae0<\/h3>\n<\/section>\n<ul class=\"lcp_catlist\" id=\"lcp_instance_0\"><li><a href=\"\/\/www.afterroberto.com\/%e4%b9%99%e5%9e%8b%e8%82%9d%e7%82%8e-%e9%a9%97%e4%b9%99%e8%82%9d-%e6%95%91%e4%bd%a0%e5%91%bd-%e8%a1%9b%e7%94%9f%e8%99%95%e6%96%b9\/\">\u3010\u4e59\u578b\u809d\u708e\u3011\u9a57\u4e59\u809d \u6551\u4f60\u547d(\u885b\u751f\u8655\u65b9)<\/a><\/li><li><a href=\"\/\/www.afterroberto.com\/%e9%80%86%e8%bd%89%e8%84%82%e8%82%aa%e8%82%9d%e6%9c%89%e6%b3%95%ef%bc%88%e9%a4%8a%e5%92%8c%e9%86%ab%e5%ba%a6%e7%99%be%e7%a7%91%ef%bc%89\/\">\u9006\u8f49\u8102\u80aa\u809d\u6709\u6cd5\uff08\u990a\u548c\u91ab\u5ea6\u767e\u79d1\uff09<\/a><\/li><li><a href=\"\/\/www.afterroberto.com\/%e6%b7%ba%e8%ab%87%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8ea%e8%87%b3e%ef%bc%88%e9%a4%8a%e5%92%8c%e9%86%ab%e5%ba%a6%e7%99%be%e7%a7%91%ef%bc%89\/\">\u6dfa\u8ac7\u75c5\u6bd2\u6027\u809d\u708eA\u81f3E\uff08\u990a\u548c\u91ab\u5ea6\u767e\u79d1\uff09<\/a><\/li><li><a href=\"\/\/www.afterroberto.com\/%e3%80%90%e8%82%9d%e7%82%8e%e8%88%87%e8%82%9d%e7%99%8c%e3%80%91-%e6%8f%9b%e8%82%9d%e4%b8%8d%e6%98%93-%e3%80%8c%e4%bf%9d%e3%80%8d%e8%82%9d%e8%a6%81%e7%94%b1%e9%98%b2%e7%82%8e%e5%81%9a%e8%b5%b7\/\">\u3010\u809d\u708e\u8207\u809d\u764c\u3011 \u63db\u809d\u4e0d\u6613 \u300c\u4fdd\u300d\u809d\u8981\u7531\u9632\u708e\u505a\u8d77<\/a><\/li><li class=\"current\"><a href=\"\/\/www.afterroberto.com\/%e6%96%b0%e9%9b%bb%e7%99%82%e9%9a%94%e5%b1%b1%e6%89%93%e7%89%9b-%e6%bf%80%e6%b4%bb%e5%85%8d%e7%96%ab%e7%b3%bb%e7%b5%b1%e6%8a%97%e7%99%8c\/\">\u3010\u809d\u708e\u8207\u809d\u764c\u3011\u65b0\u96fb\u7642\u9694\u5c71\u6253\u725b \u6fc0\u6d3b\u514d\u75ab\u7cfb\u7d71\u6297\u764c<\/a><\/li><li><a href=\"\/\/www.afterroberto.com\/%e4%b8%ad%e5%a4%a7%e6%96%b0%e6%b3%95%e6%b8%9b%e8%82%9d%e7%99%8c%e7%b4%b0%e8%83%9e-%e5%8e%9f%e4%bd%8d%e5%be%a9%e7%99%bc%e6%b8%9b%e8%87%b34-8\/\">\u3010\u809d\u708e\u8207\u809d\u764c\u3011\u4e2d\u5927\u65b0\u6cd5\u6e1b\u809d\u764c\u7d30\u80de \u539f\u4f4d\u5fa9\u767c\u6e1b\u81f34.8%<\/a><\/li><li><a href=\"\/\/www.afterroberto.com\/%e4%b9%99%e8%82%9d%e5%ba%b7%e5%be%a9%e8%80%85%e4%bb%8d%e6%9c%89%e6%82%a3%e8%82%9d%e7%99%8c%e9%a2%a8%e9%9a%aa\/\">\u3010\u809d\u708e\u8207\u809d\u764c\u3011\u4e59\u809d\u5eb7\u5fa9\u8005\u4ecd\u6709\u60a3\u809d\u764c\u98a8\u96aa<\/a><\/li><li><a href=\"\/\/www.afterroberto.com\/50%e6%ad%b2%e5%be%8c%e4%b9%99%e8%82%9d%e5%ba%b7%e5%be%a9%e3%80%805%e5%b9%b4%e5%85%a7%e6%82%a3%e8%82%9d%e7%99%8c%e9%a2%a8%e9%9a%aa%e8%bc%83%e9%ab%98\/\">\u3010\u809d\u708e\u8207\u809d\u764c\u301150\u6b72\u5f8c\u4e59\u809d\u5eb7\u5fa9 5\u5e74\u5167\u60a3\u809d\u764c\u98a8\u96aa\u8f03\u9ad8<\/a><\/li><li><a href=\"\/\/www.afterroberto.com\/%e6%94%b9%e8%89%af%e9%9b%bb%e7%99%82%e7%9e%84%e6%ba%96%e8%82%9d%e7%99%8c-%e5%b0%84%e6%ad%bb%e8%85%ab%e7%98%a4-%e7%b4%93%e7%b7%a9%e6%9c%ab%e6%9c%9f%e8%8b%a6\/\">\u3010\u809d\u708e\u8207\u809d\u764c\u3011\u6539\u826f\u96fb\u7642\u7784\u6e96\u809d\u764c \u5c04\u6b7b\u816b\u7624 \u7d13\u7de9\u672b\u671f\u82e6<\/a><\/li><li><a href=\"\/\/www.afterroberto.com\/%e5%bc%b5%e6%95%ac%e8%bb%92%e4%b9%9f%e4%b8%ad%e6%8b%9b-%e9%a3%9f%e5%ae%8c%e5%94%94%e9%83%81-%e7%98%a6%e4%ba%ba%e9%83%bd%e6%9c%89%e8%84%82%e8%82%aa%e8%82%9d\/\">\u3010\u809d\u708e\u8207\u809d\u764c\u3011\u5f35\u656c\u8ed2\u4e5f\u4e2d\u62db \u98df\u5b8c\u5514\u90c1 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\u91cd\u6574\u514d\u75ab\u529b 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1\uff09\u662f\u514d\u75ab\u7d30\u80de\u8868\u9762\u7684\u86cb\u767d\u8cea\uff0c\u8ca0\u8cac\u8abf\u7bc0\u514d\u75ab\u7cfb\u7d71\u529f\u80fd\uff0c\u4ee4\u6574\u500b\u514d\u75ab\u7cfb\u7d71\u6070\u5982\u5176\u5206\u904b\u4f5c\u3002\u7136\u800c\u7576\u764c\u7d30\u80de\u8868\u9762\u7684PD-L1\u914d\u9ad4\uff0c\u8207\u514d\u75ab\u7d30\u80de\u7684PD-1\u7d50\u5408\uff0c\u4fbf\u6703\u6291\u5236\u4e86\u514d\u75ab\u7d30\u80de\u7684\u6bba\u6ec5\u80fd\u529b\uff1b\u60c5\u51b5\u604d\u5982\u764c\u7d30\u80de\u55ac\u88dd\u6210\u6b63\u5e38\u7d30\u80de\uff0c\u907f\u904e\u514d\u75ab\u7d30\u80de\u7684\u76e3\u5bdf\u3002\u800c\u514d\u75ab\u6aa2\u67e5\u7ad9\uff08PD-1\uff09\u6291\u5236\u5291\u7684\u4f5c\u7528\u4fbf\u662f\u9ecf\u5728\u514d\u75ab\u7d30\u80dePD-1\u4e4b\u4e0a\uff0c\u50cf\u4fdd\u8b77\u7f69\u822c\u963b\u6b62\u764c\u7d30\u80de\u7684PD-L1\u914d\u9ad4\u8207PD-1\u63a5\u89f8\uff0c\u4ee4\u514d\u75ab\u7d30\u80de\u4e0d\u518d\u53d7\u764c\u7d30\u80de\u6240\u6b3a\u9a19\uff0c\u91cb\u653e\u5176\u539f\u6709\u6297\u764c\u80fd\u529b\u3002 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